US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

Crescent Biopharma Inc

17.18

-1.6200-8.62%

Volume:528.88K

Turnover:9.45M

Market Cap:638.13M

PE:-2.32

High:19.26

Open:18.87

Low:17.09

Close:18.80

52wk High:27.41

52wk Low:8.72

Shares:37.14M

Float Shares:15.95M

Volume Ratio:1.89

T/O Rate:3.32%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-7.4105

EPS(LYR):-12.8150

ROE:-160.75%

ROA:-69.15%

PB:8.80

PE(LYR):-1.34

Loading ...

Overview Company News Filings

Major Issues Report

8-K - Current report

Annual Report

10-K - Annual report [Section 13 and 15(d), not S-K Item 405]

Employee Stock Ownership

S-8 - Securities to be offered to employees in employee benefit plans

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Beneficial Ownership Change

SC 13G - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13G/A [Amend] - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13G - Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Major Issues Report

8-K - Current report

Major Issues Report

8-K - Current report

Beneficial Ownership Change

SC 13D/A [Amend] - General statement of acquisition of beneficial ownership

Statement Of Changes In Beneficial Ownership

3 - Initial statement of beneficial ownership of securities

Statement Of Changes In Beneficial Ownership

4 - Statement of changes in beneficial ownership of securities

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers HK | Online Trading in stocks, bonds & ETFS","description":"Discover Tiger Brokers HK, an online trading platform for stocks&ETFs, options&futures, bonds and crypto. Open an account to enjoy low commission trading today!","keywords":"tiger trading,tiger security,tiger broker hk,tigers co ltd,tiger trade hk,tiger brokers hk,stock broker,securities broker,online brokerage,hong kong broker,hk broker,online stock trading,online trading platform,stock trading platforms,trading application,stock trading,stock trading hong kong,buying stocks in hong kong,tiger brokers","social":{"ogDescription":"Discover Tiger Brokers HK, an online trading platform for stocks&ETFs, options&futures, bonds and crypto. Open an account to enjoy low commission trading today!","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.imtigers.com/stock/CBIO/filings?page=6"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"HKG","license":"TBHK","edition":"fundamental","symbol":"CBIO","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"CBIO\",,,,,undefined,":{"symbol":"CBIO","market":"US","secType":"STK","nameCN":"Crescent Biopharma Inc","latestPrice":17.18,"timestamp":1789588800000,"preClose":18.8,"halted":0,"volume":528883,"delay":0,"changeRate":-0.0861702127659575,"floatShares":15953500,"shares":37143940,"eps":-7.4105,"marketStatus":"Pre-Mkt","change":-1.62,"latestTime":"09-17 05:34:27 EDT","open":18.87,"high":19.26,"low":17.09,"amount":9451766,"amplitude":0.115426,"askPrice":27.48,"askSize":200,"bidPrice":11.15,"bidSize":100,"shortable":3,"etf":0,"ttmEps":-7.4105,"tradingStatus":1,"nextMarketStatus":{"tag":"Open","tradingStatus":2,"beginTime":1789651800000},"marketStatusCode":1,"adr":0,"adrRate":0,"listingDate":1389330000000,"exchange":"NASDAQ","adjPreClose":17.18,"postHourTrading":{"tag":"盘后","latestPrice":17.18,"preClose":17.18,"latestTime":"17:28 EDT","volume":3654,"amount":62775.72,"timestamp":1789594113563,"change":0,"changeRate":0,"amplitude":0},"volumeRatio":1.8852986674637815,"impliedVol":0.8054,"impliedVolPercentile":0.95},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"CBIO\",,,,,undefined,":{"symbol":"CBIO","floatShares":15953500,"roa":"-69.15%","roe":"-160.75%","lyrEps":-12.814991,"volumeRatio":1.8852986674637815,"shares":37143940,"dividePrice":0,"high":19.26,"amplitude":0.115426,"preClose":18.8,"low":17.09,"week52Low":8.72,"pbRate":"8.80","psRate":"53.70","week52High":27.41,"institutionHeld":0.0724,"latestPrice":17.18,"committee":-0.333333,"eps":-7.4105,"divideRate":0,"volume":528883,"delay":0,"ttmEps":-7.4105,"open":18.87,"prevYearClose":11.86,"prevWeekClose":19.41,"prevMonthClose":16.6,"prevQuarterClose":18,"fiveDayClose":19.99,"twentyDayClose":16.69,"sixtyDayClose":17.57},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/CBIO\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-07-30","symbol":"CBIO","fiscalQuarterEnding":"2026/06","expectedEps":-0.78,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1785384000000,"reportTimeType":"pre","actualEps":-0.74},{"market":"US","date":"2026-04-29","symbol":"CBIO","fiscalQuarterEnding":"2026/03","expectedEps":-0.85,"name":null,"time":"Post-Mkt","type":"earning","dateTimestamp":1777435200000,"reportTimeType":"post","actualEps":-0.7},{"market":"US","date":"2026-02-26","symbol":"CBIO","fiscalQuarterEnding":"2025/12","expectedEps":-2.22,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1772082000000,"reportTimeType":"pre","actualEps":-4.01},{"market":"US","date":"2025-11-06","symbol":"CBIO","fiscalQuarterEnding":"2025/09","expectedEps":-1.01,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1762405200000,"reportTimeType":"pre","actualEps":-1.27},{"market":"US","date":"2025-07-31","symbol":"CBIO","fiscalQuarterEnding":"2025/06","expectedEps":-2.69,"name":null,"time":"","type":"earning","dateTimestamp":1753934400000,"reportTimeType":"","actualEps":-4.93}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"CBIO\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"CBIO\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.375,"buy":0.5,"hold":0.125,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.5,"analysts":8,"updateTime":1780372800000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/CBIO\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"CBIO","date":"2026-09-16","current":-2.318332,"percent":0.047561,"low":-7.394562,"twenty":-3.572484,"median":-0.979043,"eighty":-0.169318,"high":2.563796,"avg":-1.553944,"sd":2.166542,"marketCap":804659965},"quantilePoints":[{"date":"2021-09-17","current":-2.101704,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":162474331},{"date":"2021-09-24","current":-1.923181,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":148673422},{"date":"2021-10-01","current":-1.647282,"twenty":-4.26328,"median":-2.208025,"eighty":-1.2153,"marketCap":127344746},{"date":"2021-10-08","current":-1.562077,"twenty":-4.254957,"median":-2.206531,"eighty":-1.215339,"marketCap":120757948},{"date":"2021-10-15","current":-1.622937,"twenty":-4.254957,"median":-2.206531,"eighty":-1.215339,"marketCap":125462804},{"date":"2021-10-22","current":-1.407898,"twenty":-4.254957,"median":-2.206531,"eighty":-1.215339,"marketCap":108838982},{"date":"2021-10-29","current":-1.334866,"twenty":-4.254957,"median":-2.206531,"eighty":-1.217573,"marketCap":103193156},{"date":"2021-11-05","current":-1.253719,"twenty":-4.254957,"median":-2.206531,"eighty":-1.230021,"marketCap":96920016},{"date":"2021-11-12","current":-0.620853,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":53710598},{"date":"2021-11-19","current":-0.475624,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":41146716},{"date":"2021-11-26","current":-0.45384,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":39262133},{"date":"2021-12-03","current":-0.395748,"twenty":-4.254957,"median":-2.206531,"eighty":-1.236189,"marketCap":34236580},{"date":"2021-12-10","current":-0.395748,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":34236580},{"date":"2021-12-17","current":-0.366703,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":31723804},{"date":"2021-12-23","current":-0.384856,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":33294289},{"date":"2021-12-31","current":-0.331848,"twenty":-4.246633,"median":-2.205037,"eighty":-1.233979,"marketCap":28708472},{"date":"2022-01-07","current":-0.303637,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":26267937},{"date":"2022-01-14","current":-0.284866,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":24644056},{"date":"2022-01-21","current":-0.232366,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20102212},{"date":"2022-01-28","current":-0.200125,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":17313030},{"date":"2022-02-04","current":-0.201832,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":17460656},{"date":"2022-02-11","current":-0.189306,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":16377021},{"date":"2022-02-18","current":-0.215955,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":18682493},{"date":"2022-02-25","current":-0.217371,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":18804991},{"date":"2022-03-04","current":-0.241552,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20896878},{"date":"2022-03-11","current":-0.236287,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20441437},{"date":"2022-03-18","current":-0.243403,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":21057067},{"date":"2022-03-25","current":-0.248813,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":21525072},{"date":"2022-04-01","current":-0.236294,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":20778002},{"date":"2022-04-08","current":-0.219111,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":19267104},{"date":"2022-04-14","current":-0.194197,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":17076301},{"date":"2022-04-22","current":-0.20762,"twenty":-4.23831,"median":-2.203543,"eighty":-1.231714,"marketCap":18256690},{"date":"2022-04-29","current":-0.171466,"twenty":-4.23831,"median":-2.203543,"eighty":-1.225062,"marketCap":15077508},{"date":"2022-05-06","current":-0.175797,"twenty":-4.23831,"median":-2.203543,"eighty":-1.212181,"marketCap":15458380},{"date":"2022-05-13","current":-0.141671,"twenty":-4.23831,"median":-2.203543,"eighty":-1.209147,"marketCap":11338034},{"date":"2022-05-20","current":-0.149458,"twenty":-4.23831,"median":-2.203543,"eighty":-1.209147,"marketCap":11961280},{"date":"2022-05-27","current":-0.483772,"twenty":-4.23831,"median":-2.203543,"eighty":-1.209147,"marketCap":38716775},{"date":"2022-06-03","current":-0.491638,"twenty":-4.23831,"median":-2.203543,"eighty":-1.206318,"marketCap":39346316},{"date":"2022-06-10","current":-0.538836,"twenty":-4.23831,"median":-2.203543,"eighty":-1.206318,"marketCap":43123562},{"date":"2022-06-17","current":-0.570301,"twenty":-4.23831,"median":-2.203543,"eighty":-1.204728,"marketCap":45641726},{"date":"2022-06-24","current":-0.593899,"twenty":-4.246633,"median":-2.205037,"eighty":-1.203969,"marketCap":47530350},{"date":"2022-07-01","current":-0.704026,"twenty":-4.246633,"median":-2.205037,"eighty":-1.190642,"marketCap":56343924},{"date":"2022-07-08","current":-0.711892,"twenty":-4.246633,"median":-2.205037,"eighty":-1.183449,"marketCap":56973465},{"date":"2022-07-15","current":-0.688294,"twenty":-4.246633,"median":-2.205037,"eighty":-1.17379,"marketCap":55084842},{"date":"2022-07-22","current":-0.688294,"twenty":-4.246633,"median":-2.205037,"eighty":-1.166615,"marketCap":55084842},{"date":"2022-07-29","current":-0.688294,"twenty":-4.246633,"median":-2.205037,"eighty":-1.164065,"marketCap":55084842},{"date":"2022-08-05","current":-0.735491,"twenty":-4.246633,"median":-2.205037,"eighty":-1.164065,"marketCap":58862089},{"date":"2022-08-12","current":-0.755157,"twenty":-4.246633,"median":-2.205037,"eighty":-1.164065,"marketCap":60435941},{"date":"2022-08-19","current":-7.394562,"twenty":-4.319663,"median":-2.219417,"eighty":-1.173236,"marketCap":62639335},{"date":"2022-08-26","current":-6.948659,"twenty":-4.374472,"median":-2.231928,"eighty":-1.186522,"marketCap":58862089},{"date":"2022-09-02","current":-7.245928,"twenty":-4.467447,"median":-2.249855,"eighty":-1.198454,"marketCap":61380253},{"date":"2022-09-09","current":-7.245928,"twenty":-4.558156,"median":-2.284285,"eighty":-1.205949,"marketCap":61380253},{"date":"2022-09-16","current":-7.283086,"twenty":-4.607295,"median":-2.335818,"eighty":-1.223882,"marketCap":61695023},{"date":"2022-09-23","current":-1.818542,"twenty":-4.702259,"median":-2.339886,"eighty":-1.237407,"marketCap":15404869},{"date":"2022-09-30","current":-1.872794,"twenty":-4.702259,"median":-2.339886,"eighty":-1.24606,"marketCap":15864434},{"date":"2022-10-07","current":-1.9891,"twenty":-4.702259,"median":-2.339886,"eighty":-1.250381,"marketCap":16849666},{"date":"2022-10-14","current":-2.235462,"twenty":-4.702259,"median":-2.339886,"eighty":-1.264627,"marketCap":18936595},{"date":"2022-10-21","current":-2.143308,"twenty":-4.702259,"median":-2.339886,"eighty":-1.287061,"marketCap":18155964},{"date":"2022-10-28","current":-2.158172,"twenty":-4.702259,"median":-2.339886,"eighty":-1.31186,"marketCap":18281872},{"date":"2022-11-04","current":-2.07345,"twenty":-4.702259,"median":-2.339886,"eighty":-1.333243,"marketCap":17564195},{"date":"2022-11-11","current":-2.064904,"twenty":-4.702259,"median":-2.339886,"eighty":-1.341215,"marketCap":17491798},{"date":"2022-11-18","current":1.47314,"twenty":-4.702259,"median":-2.339886,"eighty":-1.340298,"marketCap":17505320},{"date":"2022-11-25","current":1.457505,"twenty":-4.702259,"median":-2.339886,"eighty":-1.333243,"marketCap":17319529},{"date":"2022-12-02","current":1.457505,"twenty":-4.702259,"median":-2.339886,"eighty":-1.31186,"marketCap":17319529},{"date":"2022-12-09","current":1.350444,"twenty":-4.702259,"median":-2.339886,"eighty":-1.287061,"marketCap":16047331},{"date":"2022-12-16","current":1.319704,"twenty":-4.702259,"median":-2.33949,"eighty":-1.264627,"marketCap":15682046},{"date":"2022-12-23","current":1.332954,"twenty":-4.702259,"median":-2.284285,"eighty":-1.246705,"marketCap":15839496},{"date":"2022-12-30","current":1.397879,"twenty":-4.702259,"median":-2.249855,"eighty":-1.238056,"marketCap":16611002},{"date":"2023-01-06","current":2.033511,"twenty":-4.702259,"median":-2.235462,"eighty":-1.228022,"marketCap":24164207},{"date":"2023-01-13","current":0.834057,"twenty":-4.702259,"median":-2.228683,"eighty":-1.205599,"marketCap":9911100},{"date":"2023-01-20","current":0.847084,"twenty":-4.603457,"median":-2.215921,"eighty":-1.195389,"marketCap":10065902},{"date":"2023-01-27","current":0.937321,"twenty":-4.472686,"median":-2.202049,"eighty":-1.178581,"marketCap":11138189},{"date":"2023-02-03","current":0.926201,"twenty":-4.288569,"median":-2.18711,"eighty":-1.155134,"marketCap":11006041},{"date":"2023-02-10","current":0.79434,"twenty":-4.214316,"median":-2.168359,"eighty":-1.126768,"marketCap":9439143},{"date":"2023-02-17","current":0.798471,"twenty":-4.189559,"median":-2.158428,"eighty":-0.733918,"marketCap":9488227},{"date":"2023-02-24","current":0.76352,"twenty":-4.166469,"median":-2.154549,"eighty":-0.722119,"marketCap":9072904},{"date":"2023-03-03","current":0.752081,"twenty":-4.104269,"median":-2.149915,"eighty":-0.702453,"marketCap":8936981},{"date":"2023-03-10","current":0.629435,"twenty":-4.033134,"median":-2.136015,"eighty":-0.69852,"marketCap":7479577},{"date":"2023-03-17","current":0.621492,"twenty":-4.001878,"median":-2.108214,"eighty":-0.69616,"marketCap":7385185},{"date":"2023-03-24","current":0.660891,"twenty":-3.965473,"median":-2.07345,"eighty":-0.690654,"marketCap":7853367},{"date":"2023-03-31","current":-0.948348,"twenty":-3.915415,"median":-2.065977,"eighty":-0.688294,"marketCap":7816283},{"date":"2023-04-06","current":-0.959343,"twenty":-3.889599,"median":-2.052815,"eighty":-0.688294,"marketCap":7906907},{"date":"2023-04-14","current":-1.006532,"twenty":-3.827716,"median":-2.025144,"eighty":-0.688294,"marketCap":8295833},{"date":"2023-04-21","current":-1.094952,"twenty":-3.800801,"median":-2.009658,"eighty":-0.688294,"marketCap":9024598},{"date":"2023-04-28","current":-1.035394,"twenty":-3.762866,"median":-1.990699,"eighty":-0.688294,"marketCap":8533720},{"date":"2023-05-05","current":-0.984999,"twenty":-3.721769,"median":-1.979984,"eighty":-0.688294,"marketCap":8118362},{"date":"2023-05-12","current":-1.034936,"twenty":-3.659217,"median":-1.959683,"eighty":-0.688294,"marketCap":8529944},{"date":"2023-05-19","current":1.307824,"twenty":-3.590813,"median":-1.953003,"eighty":-0.62356,"marketCap":8571480},{"date":"2023-05-26","current":1.269223,"twenty":-3.551824,"median":-1.941439,"eighty":-0.593899,"marketCap":8318489},{"date":"2023-06-02","current":1.225437,"twenty":-3.52457,"median":-1.933362,"eighty":-0.561113,"marketCap":8031514},{"date":"2023-06-09","current":1.293997,"twenty":-3.472925,"median":-1.931296,"eighty":-0.53097,"marketCap":8480856},{"date":"2023-06-16","current":1.429965,"twenty":-3.448626,"median":-1.923181,"eighty":-0.522991,"marketCap":9371988},{"date":"2023-06-23","current":1.832106,"twenty":-3.404905,"median":-1.909241,"eighty":-0.488682,"marketCap":12007624},{"date":"2023-06-30","current":1.947333,"twenty":-3.388492,"median":-1.894612,"eighty":-0.479372,"marketCap":12762820},{"date":"2023-07-07","current":1.958856,"twenty":-3.336284,"median":-1.890722,"eighty":-0.461086,"marketCap":12838340},{"date":"2023-07-14","current":2.017045,"twenty":-3.28054,"median":-1.87855,"eighty":-0.435864,"marketCap":13219714},{"date":"2023-07-21","current":2.369063,"twenty":-3.21113,"median":-1.860968,"eighty":-0.410271,"marketCap":15526840},{"date":"2023-07-28","current":2.082724,"twenty":-3.161463,"median":-1.848291,"eighty":-0.373238,"marketCap":13650176},{"date":"2023-08-04","current":2.074083,"twenty":-3.143393,"median":-1.84,"eighty":-0.35976,"marketCap":13593537},{"date":"2023-08-11","current":1.957703,"twenty":-3.125944,"median":-1.827398,"eighty":-0.343256,"marketCap":12830788},{"date":"2023-08-18","current":-0.381172,"twenty":-3.078872,"median":-1.818996,"eighty":-0.332284,"marketCap":18124716},{"date":"2023-08-25","current":-0.415288,"twenty":-3.029373,"median":-1.817905,"eighty":-0.332284,"marketCap":19746943},{"date":"2023-09-01","current":-0.446994,"twenty":-2.989657,"median":-1.810594,"eighty":-0.332284,"marketCap":21254547},{"date":"2023-09-08","current":-0.420639,"twenty":-2.973696,"median":-1.810594,"eighty":-0.332284,"marketCap":20001375},{"date":"2023-09-15","current":-0.445556,"twenty":-2.960128,"median":-1.795851,"eighty":-0.332284,"marketCap":21186192},{"date":"2023-09-22","current":-0.394524,"twenty":-2.933767,"median":-1.789589,"eighty":-0.332284,"marketCap":18759596},{"date":"2023-09-29","current":-0.391329,"twenty":-2.919659,"median":-1.782149,"eighty":-0.332284,"marketCap":18607697},{"date":"2023-10-06","current":-0.343411,"twenty":-2.899577,"median":-1.776987,"eighty":-0.332284,"marketCap":16329203},{"date":"2023-10-13","current":-0.327439,"twenty":-2.883682,"median":-1.764944,"eighty":-0.328321,"marketCap":15569705},{"date":"2023-10-20","current":-0.320251,"twenty":-2.87071,"median":-1.755982,"eighty":-0.319653,"marketCap":15227931},{"date":"2023-10-27","current":-0.430462,"twenty":-2.848433,"median":-1.751781,"eighty":-0.315974,"marketCap":20468466},{"date":"2025-06-17","current":-0.345681,"twenty":-2.587053,"median":-1.08579,"eighty":-0.175718,"marketCap":10192829},{"date":"2025-07-25","current":-2.530939,"twenty":-2.520186,"median":-0.984999,"eighty":-0.169604,"marketCap":180881157},{"date":"2025-08-01","current":-2.414306,"twenty":-2.512378,"median":-0.984999,"eighty":-0.169604,"marketCap":172545620},{"date":"2025-08-08","current":-2.138274,"twenty":-2.502835,"median":-0.984999,"eighty":-0.169604,"marketCap":152818182},{"date":"2025-08-15","current":-2.707833,"twenty":-2.507436,"median":-0.984999,"eighty":-0.169604,"marketCap":193523388},{"date":"2025-08-22","current":-3.939042,"twenty":-2.518451,"median":-0.984999,"eighty":-0.169604,"marketCap":281515449},{"date":"2025-08-29","current":-3.870656,"twenty":-2.533218,"median":-0.984999,"eighty":-0.169604,"marketCap":276628028},{"date":"2025-09-05","current":-3.744825,"twenty":-2.546538,"median":-0.982021,"eighty":-0.169461,"marketCap":267635173},{"date":"2025-09-12","current":-3.432984,"twenty":-2.56751,"median":-0.984999,"eighty":-0.169604,"marketCap":245348534},{"date":"2025-09-19","current":-3.539667,"twenty":-2.58242,"median":-0.984999,"eighty":-0.169604,"marketCap":252972910},{"date":"2025-09-26","current":-3.394688,"twenty":-2.593613,"median":-0.984999,"eighty":-0.169604,"marketCap":242611578},{"date":"2025-10-03","current":-3.290741,"twenty":-2.627618,"median":-0.984999,"eighty":-0.169604,"marketCap":235182698},{"date":"2025-10-10","current":-3.356392,"twenty":-2.661594,"median":-0.984999,"eighty":-0.169604,"marketCap":239874622},{"date":"2025-10-17","current":-3.378276,"twenty":-2.67655,"median":-0.984999,"eighty":-0.169604,"marketCap":241438597},{"date":"2025-10-24","current":-3.498635,"twenty":-2.689355,"median":-0.984999,"eighty":-0.169604,"marketCap":250040458},{"date":"2025-10-31","current":-3.422043,"twenty":-2.698677,"median":-0.984999,"eighty":-0.169604,"marketCap":244566546},{"date":"2025-11-07","current":-3.583434,"twenty":-2.742274,"median":-0.984999,"eighty":-0.169604,"marketCap":256100860},{"date":"2025-11-14","current":-3.5506,"twenty":-2.768258,"median":-0.984999,"eighty":-0.169604,"marketCap":253754301},{"date":"2025-11-21","current":-3.577955,"twenty":-2.801418,"median":-0.984999,"eighty":-0.169604,"marketCap":255709265},{"date":"2025-11-28","current":-4.116836,"twenty":-2.807709,"median":-0.984999,"eighty":-0.169604,"marketCap":294222051},{"date":"2025-12-05","current":-3.553336,"twenty":-2.825536,"median":-0.984999,"eighty":-0.169604,"marketCap":253949797},{"date":"2025-12-12","current":-4.187958,"twenty":-2.846705,"median":-0.984999,"eighty":-0.169604,"marketCap":299304957},{"date":"2025-12-19","current":-3.342707,"twenty":-2.846705,"median":-0.984999,"eighty":-0.169604,"marketCap":238896576},{"date":"2025-12-26","current":-3.383738,"twenty":-2.870518,"median":-0.984999,"eighty":-0.169604,"marketCap":241829022},{"date":"2026-01-02","current":-3.244231,"twenty":-2.887152,"median":-0.984999,"eighty":-0.169604,"marketCap":231858706},{"date":"2026-01-09","current":-3.000777,"twenty":-2.947456,"median":-0.984999,"eighty":-0.169604,"marketCap":214459528},{"date":"2026-01-16","current":-3.419299,"twenty":-2.997495,"median":-0.984999,"eighty":-0.169604,"marketCap":244370475},{"date":"2026-01-23","current":-3.728404,"twenty":-3.025943,"median":-0.984999,"eighty":-0.169604,"marketCap":266461565},{"date":"2026-01-30","current":-2.775103,"twenty":-3.025943,"median":-0.984999,"eighty":-0.169604,"marketCap":198331077},{"date":"2026-02-06","current":-2.574048,"twenty":-2.983248,"median":-0.984999,"eighty":-0.169604,"marketCap":183962093},{"date":"2026-02-13","current":-2.524811,"twenty":-2.910905,"median":-0.984999,"eighty":-0.169604,"marketCap":180443158},{"date":"2026-02-20","current":-3.211406,"twenty":-2.875674,"median":-0.984999,"eighty":-0.169604,"marketCap":229512750},{"date":"2026-02-27","current":-3.3769,"twenty":-2.875674,"median":-0.984999,"eighty":-0.169604,"marketCap":241340281},{"date":"2026-03-06","current":-2.444514,"twenty":-2.837274,"median":-0.984999,"eighty":-0.169604,"marketCap":376313362},{"date":"2026-03-13","current":-2.494138,"twenty":-2.807709,"median":-0.984999,"eighty":-0.169604,"marketCap":383952556},{"date":"2026-03-20","current":-2.291327,"twenty":-2.77895,"median":-0.984999,"eighty":-0.169604,"marketCap":352731501},{"date":"2026-03-27","current":-2.912704,"twenty":-2.749773,"median":-0.984999,"eighty":-0.169604,"marketCap":448387501},{"date":"2026-04-02","current":-4.168403,"twenty":-2.768258,"median":-0.984999,"eighty":-0.169604,"marketCap":641692335},{"date":"2026-04-10","current":-4.120937,"twenty":-2.768258,"median":-0.984999,"eighty":-0.169604,"marketCap":634385279},{"date":"2026-04-17","current":-4.196452,"twenty":-2.77895,"median":-0.984999,"eighty":-0.169604,"marketCap":646010141},{"date":"2026-04-24","current":-5.544926,"twenty":-2.829031,"median":-0.984999,"eighty":-0.169604,"marketCap":853596947},{"date":"2026-05-01","current":-4.828663,"twenty":-2.944974,"median":-0.984999,"eighty":-0.169604,"marketCap":743334005},{"date":"2026-05-08","current":-3.690363,"twenty":-3.025943,"median":-0.984999,"eighty":-0.169604,"marketCap":598123026},{"date":"2026-05-15","current":-4.352579,"twenty":-3.088318,"median":-0.984999,"eighty":-0.169604,"marketCap":705452880},{"date":"2026-05-22","current":-4.147558,"twenty":-3.181319,"median":-0.984999,"eighty":-0.169604,"marketCap":672223823},{"date":"2026-05-29","current":-4.401783,"twenty":-3.236025,"median":-0.982021,"eighty":-0.169461,"marketCap":713427853},{"date":"2026-06-05","current":-3.782622,"twenty":-3.282788,"median":-0.984999,"eighty":-0.169604,"marketCap":613076101},{"date":"2026-06-12","current":-3.76007,"twenty":-3.344356,"median":-0.984999,"eighty":-0.169604,"marketCap":609420905},{"date":"2026-06-18","current":-3.733418,"twenty":-3.377721,"median":-0.984999,"eighty":-0.169604,"marketCap":605101127},{"date":"2026-06-26","current":-3.483293,"twenty":-3.392498,"median":-0.982021,"eighty":-0.169461,"marketCap":564561678},{"date":"2026-07-02","current":-3.501745,"twenty":-3.405077,"median":-0.982021,"eighty":-0.169461,"marketCap":567552293},{"date":"2026-07-10","current":-3.436138,"twenty":-3.419305,"median":-0.982021,"eighty":-0.169461,"marketCap":556918995},{"date":"2026-07-17","current":-3.097855,"twenty":-3.419307,"median":-0.982021,"eighty":-0.169461,"marketCap":502091051},{"date":"2026-07-24","current":-4.342042,"twenty":-3.429702,"median":-0.982021,"eighty":-0.169461,"marketCap":703745165},{"date":"2026-07-31","current":-3.829564,"twenty":-3.446389,"median":-0.979043,"eighty":-0.169318,"marketCap":620684227},{"date":"2026-08-07","current":-4.258748,"twenty":-3.477142,"median":-0.979043,"eighty":-0.169318,"marketCap":703221448},{"date":"2026-08-14","current":-4.310589,"twenty":-3.491494,"median":-0.979043,"eighty":-0.169318,"marketCap":711781661},{"date":"2026-08-21","current":-4.206907,"twenty":-3.503795,"median":-0.979043,"eighty":-0.169318,"marketCap":694661236},{"date":"2026-08-28","current":-4.603491,"twenty":-3.542402,"median":-0.979043,"eighty":-0.169318,"marketCap":760146861},{"date":"2026-09-04","current":-5.287794,"twenty":-3.55505,"median":-0.979043,"eighty":-0.169318,"marketCap":873141664},{"date":"2026-09-11","current":-5.044141,"twenty":-3.561542,"median":-0.979043,"eighty":-0.169318,"marketCap":832908666},{"date":"2026-09-16","current":-4.873065,"twenty":-3.572484,"median":-0.979043,"eighty":-0.169318,"marketCap":804659965}],"updateTime":1789637667331},"$inf$@#url:\"https://stock-news.skytigris.cn/v3/notice/important/events/list\",params:#symbol:\"CBIO\",pageSize:20,pageCount:6,market:\"us\",,,undefined,":[{"items":[{"cdn_pdf":false,"hasAttachments":true,"id":"14556807","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522095321-CBIO","pdf_url":"","pub_time":1649088000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/0001193125-22-095321-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 2.05: Cost Associated with Exit or Disposal Activities;\nItem 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-10.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223dex101.htm","primary":true,"translateUrl":"","linkName":"d313223dex101.htm","type":"EX-10.1","id":"NTFILEDEHW7S3yq1sm4M8w","market":"us","size":27543},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223d8k.htm","primary":false,"translateUrl":"","linkName":"d313223d8k.htm","type":"8-K","id":"NTFILEGgPYXqLTLDQUvo1q","market":"us","size":33341},{"description":"EX-10.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223dex102.htm","primary":false,"translateUrl":"","linkName":"d313223dex102.htm","type":"EX-10.2","id":"NTFILEGhxasT7NqpGTmxCA","market":"us","size":11275},{"description":"EX-99.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/d313223dex991.htm","primary":false,"translateUrl":"","linkName":"d313223dex991.htm","type":"EX-99.1","id":"NTFILE5jeAc1mk78EM3eSv","market":"us","size":58092},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/g313223dsp001.jpg","primary":false,"translateUrl":"","linkName":"g313223dsp001.jpg","type":"GRAPHIC","id":"NTFILEHzb914A84rrShdfJ","market":"us","size":4231},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522095321/g313223g0405021300120.jpg","primary":false,"translateUrl":"","linkName":"g313223g0405021300120.jpg","type":"GRAPHIC","id":"NTFILE3XVgBQWTJVqaYiZ8","market":"us","size":8804}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-04-05 00:00","pubTimestamp":1649088000,"title_zh":"8-K  - Current report","summary_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 2.05: Cost Associated with Exit or Disposal Activities;\nItem 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14517465","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459022012877-CBIO","pdf_url":"","pub_time":1648656000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","symbol":"CBIO","title":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","titleType":"Annual Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/0001564590-22-012877-index.htm","us_notice_code":"Form 10-K","us_title_en":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-10k_20211231.htm","primary":true,"translateUrl":"","linkName":"cbio-10k_20211231.htm","type":"10-K","id":"NTFILECB4L9n75hhRE9SHi","market":"us","size":2732531},{"description":"EX-10.8","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex108_9.htm","primary":false,"translateUrl":"","linkName":"cbio-ex108_9.htm","type":"EX-10.8","id":"NTFILEGBb7ypNE2vXMitsD","market":"us","size":72186},{"description":"EX-23.1","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex231_8.htm","primary":false,"translateUrl":"","linkName":"cbio-ex231_8.htm","type":"EX-23.1","id":"NTFILE64EGve9vsXgGYw94","market":"us","size":3867},{"description":"EX-31.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex311_11.htm","primary":false,"translateUrl":"","linkName":"cbio-ex311_11.htm","type":"EX-31.1","id":"NTFILE5tbvhjHHmd1tfT4d","market":"us","size":17802},{"description":"EX-31.2","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex312_6.htm","primary":false,"translateUrl":"","linkName":"cbio-ex312_6.htm","type":"EX-31.2","id":"NTFILEGGerxbBw59ZedhKj","market":"us","size":17690},{"description":"EX-32.1","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex321_7.htm","primary":false,"translateUrl":"","linkName":"cbio-ex321_7.htm","type":"EX-32.1","id":"NTFILECzAUNPeK2udRCcoE","market":"us","size":5338},{"description":"EX-32.2","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/cbio-ex322_10.htm","primary":false,"translateUrl":"","linkName":"cbio-ex322_10.htm","type":"EX-32.2","id":"NTFILECS4MtedtEZzqMiPM","market":"us","size":5279},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/guycyz0ib1ig000001.jpg","primary":false,"translateUrl":"","linkName":"guycyz0ib1ig000001.jpg","type":"GRAPHIC","id":"NTFILEG4o1SaG7iSudFgmS","market":"us","size":130550},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/guycyz0ib1ig000002.jpg","primary":false,"translateUrl":"","linkName":"guycyz0ib1ig000002.jpg","type":"GRAPHIC","id":"NTFILE28AP3hsTgeYu2613","market":"us","size":238619},{"description":"GRAPHIC","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000156459022012877/guycyz0ib1ig000003.jpg","primary":false,"translateUrl":"","linkName":"guycyz0ib1ig000003.jpg","type":"GRAPHIC","id":"NTFILEGewBFtrnzqGYaDcC","market":"us","size":130550}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Annual Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Annual Report","pubTime":"2022-03-31 00:00","pubTimestamp":1648656000,"title_zh":"10-K  - Annual report [Section 13 and 15(d), not S-K Item 405","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14517464","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522091897-CBIO","pdf_url":"","pub_time":1648656000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"S-8  - Securities to be offered to employees in employee benefit plans","symbol":"CBIO","title":"S-8  - Securities to be offered to employees in employee benefit plans","titleType":"Employee Stock Ownership","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522091897/0001193125-22-091897-index.htm","us_notice_code":"Form S-8","us_title_en":"S-8  - Securities to be offered to employees in employee benefit plans","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"S-8","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522091897/d328688ds8.htm","primary":true,"translateUrl":"","linkName":"d328688ds8.htm","type":"S-8","id":"NTFILE4xsnMhgkFmhXCSbw","market":"us","size":29203},{"description":"EX-5.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522091897/d328688dex51.htm","primary":false,"translateUrl":"","linkName":"d328688dex51.htm","type":"EX-5.1","id":"NTFILE9ijcSnY5S7hXjCij","market":"us","size":8646},{"description":"EX-23.1","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522091897/d328688dex231.htm","primary":false,"translateUrl":"","linkName":"d328688dex231.htm","type":"EX-23.1","id":"NTFILEG3sSPdJjYke63XNE","market":"us","size":1559},{"description":"EX-FILING FEES","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522091897/d328688dexfilingfees.htm","primary":false,"translateUrl":"","linkName":"d328688dexfilingfees.htm","type":"EX-FILING FEES","id":"NTFILE7E927LGfLhdzFmxh","market":"us","size":26307},{"description":"GRAPHIC","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522091897/g328688g0331000350345.jpg","primary":false,"translateUrl":"","linkName":"g328688g0331000350345.jpg","type":"GRAPHIC","id":"NTFILE4pf9txoTYpr1gWB9","market":"us","size":2356}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Employee Stock Ownership","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Employee Stock Ownership","pubTime":"2022-03-31 00:00","pubTimestamp":1648656000,"title_zh":"S-8  - Securities to be offered to employees in employee benefit plans","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14382309","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522076406-CBIO","pdf_url":"","pub_time":1647360000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522076406/0001193125-22-076406-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 1.02: Termination of a Material Definitive Agreement;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522076406/d324168dex991.htm","primary":true,"translateUrl":"","linkName":"d324168dex991.htm","type":"EX-99.1","id":"NTFILE9qSsKQm9xSdbsePc","market":"us","size":6558},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522076406/d324168d8k.htm","primary":false,"translateUrl":"","linkName":"d324168d8k.htm","type":"8-K","id":"NTFILEEdaHDomRq3BJEpda","market":"us","size":24558},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522076406/g324168page1.jpg","primary":false,"translateUrl":"","linkName":"g324168page1.jpg","type":"GRAPHIC","id":"NTFILEBnTwaLAbCT1D3NUy","market":"us","size":5116}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-03-16 00:00","pubTimestamp":1647360000,"title_zh":"8-K  - Current report","summary_en":"Item 1.02: Termination of a Material Definitive Agreement;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14382308","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000194-CBIO","pdf_url":"","pub_time":1647360000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000194/0001171520-22-000194-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000194/eps10128.htm","primary":true,"translateUrl":"","linkName":"eps10128.htm","type":"SC 13D/A","id":"NTFILEJE8JBT7qffMjWFfh","market":"us","size":142681}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-03-16 00:00","pubTimestamp":1647360000,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14332452","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000185-CBIO","pdf_url":"","pub_time":1646582400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000185/0001171520-22-000185-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000185/eps10121.htm","primary":true,"translateUrl":"","linkName":"eps10121.htm","type":"SC 13D/A","id":"NTFILE6V4jK2wydV9SWp1y","market":"us","size":662937},{"description":"JOINT FILING AND SOLICITATION AGREEMENT","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000185/ex99-1.htm","primary":false,"translateUrl":"","linkName":"ex99-1.htm","type":"EX-99","id":"NTFILE33RSgatLFKYRXPEZ","market":"us","size":18493},{"description":"FORM OF NOMINEE INDEMNIFICATION AGREEMENT","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000185/ex99-2.htm","primary":false,"translateUrl":"","linkName":"ex99-2.htm","type":"EX-99","id":"NTFILEEwNvKHcP4bKke9o6","market":"us","size":10945},{"description":"FORM OF POWER OF ATTORNEY","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000185/ex99-3.htm","primary":false,"translateUrl":"","linkName":"ex99-3.htm","type":"EX-99","id":"NTFILE5EpnWp2QGmGqYC96","market":"us","size":7270}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-03-07 00:00","pubTimestamp":1646582400,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14309355","market":"us","labels":[],"media":"sec.gov","original_id":"AN93583622000227-CBIO","pdf_url":"","pub_time":1646323200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","symbol":"CBIO","title":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000093583622000227/0000935836-22-000227-index.htm","us_notice_code":"Form SC 13G","us_title_en":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1105806/000093583622000227/catalystbiosciences13g.htm","primary":true,"translateUrl":"","linkName":"catalystbiosciences13g.htm","type":"SC 13G","id":"NTFILEBB8juSZkLDzqiyxE","market":"us","size":28843}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-03-04 00:00","pubTimestamp":1646323200,"title_zh":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14279833","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000167-CBIO","pdf_url":"","pub_time":1645977600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000167/0001171520-22-000167-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000167/eps10114.htm","primary":true,"translateUrl":"","linkName":"eps10114.htm","type":"SC 13D/A","id":"NTFILE6CKUZCskxUAp2oGL","market":"us","size":130234}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-02-28 00:00","pubTimestamp":1645977600,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14251230","market":"us","labels":[],"media":"sec.gov","original_id":"AN117152022000147-CBIO","pdf_url":"","pub_time":1645545600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000147/0001171520-22-000147-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000147/eps10100.htm","primary":true,"translateUrl":"","linkName":"eps10100.htm","type":"SC 13D/A","id":"NTFILE84HQDGoPGLSHXcf9","market":"us","size":138993},{"description":"JOINT FILING AGREEMENT","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000117152022000147/ex99-1.htm","primary":false,"translateUrl":"","linkName":"ex99-1.htm","type":"EX-99.1","id":"NTFILEEdNPWAWfisLikXkm","market":"us","size":6548}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-02-23 00:00","pubTimestamp":1645545600,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14251231","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522046614-CBIO","pdf_url":"","pub_time":1645113600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522046614/0001193125-22-046614-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 3.01: Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522046614/d319094d8k.htm","primary":true,"translateUrl":"","linkName":"d319094d8k.htm","type":"8-K","id":"NTFILE4RB5xwcJPjggHtYb","market":"us","size":23597}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-02-18 00:00","pubTimestamp":1645113600,"title_zh":"8-K  - Current report","summary_en":"Item 3.01: Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14251237","market":"us","labels":[],"media":"sec.gov","original_id":"AN93583622000109-CBIO","pdf_url":"","pub_time":1644768000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"CBIO","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000093583622000109/0000935836-22-000109-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000093583622000109/catalystbio13g2022.htm","primary":true,"translateUrl":"","linkName":"catalystbio13g2022.htm","type":"SC 13G/A","id":"NTFILE9ucUweeyGC5fpmdF","market":"us","size":59351}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-02-14 00:00","pubTimestamp":1644768000,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14251236","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465922021623-CBIO","pdf_url":"","pub_time":1644768000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"CBIO","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922021623/0001104659-22-021623-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13G/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922021623/tm222623d9_sc13ga.htm","primary":true,"translateUrl":"","linkName":"tm222623d9_sc13ga.htm","type":"SC 13G/A","id":"NTFILE8JTrkiV9tSyeM3kR","market":"us","size":44414}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-02-14 00:00","pubTimestamp":1644768000,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14251235","market":"us","labels":[],"media":"sec.gov","original_id":"AN93583622000176-CBIO","pdf_url":"","pub_time":1644768000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","symbol":"CBIO","title":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000093583622000176/0000935836-22-000176-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000093583622000176/catalyst13ga1.htm","primary":true,"translateUrl":"","linkName":"catalyst13ga1.htm","type":"SC 13G/A","id":"NTFILE3cc2kqkc2LhdccAt","market":"us","size":36312}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-02-14 00:00","pubTimestamp":1644768000,"title_zh":"SC 13G/A [Amend]  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14170928","market":"us","labels":[],"media":"sec.gov","original_id":"AN94787122000195-CBIO","pdf_url":"","pub_time":1644508800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","symbol":"CBIO","title":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000094787122000195/0000947871-22-000195-index.htm","us_notice_code":"Form SC 13G","us_title_en":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SCHEDULE 13G","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1055951/000094787122000195/ss792072_sc13g.htm","primary":true,"translateUrl":"","linkName":"ss792072_sc13g.htm","type":"SC 13G","id":"NTFILEBGvJYWduY3ewExKn","market":"us","size":56171},{"description":"JOINT FILING AGREEMENT","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1055951/000094787122000195/ss792072_ex99a.htm","primary":false,"translateUrl":"","linkName":"ss792072_ex99a.htm","type":"EX-99.A","id":"NTFILEFwDHp3nFY81GMxSr","market":"us","size":7399}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-02-11 00:00","pubTimestamp":1644508800,"title_zh":"SC 13G  - Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14170929","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465922008147-CBIO","pdf_url":"","pub_time":1643212800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922008147/0001104659-22-008147-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13D/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922008147/tm224625d1_sc13da.htm","primary":true,"translateUrl":"","linkName":"tm224625d1_sc13da.htm","type":"SC 13D/A","id":"NTFILE6stfHwe68LQhxz9F","market":"us","size":128274},{"description":"EXHIBIT 99.4","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922008147/tm224625d1_ex99-4.htm","primary":false,"translateUrl":"","linkName":"tm224625d1_ex99-4.htm","type":"EX-99.4","id":"NTFILE21bsVJWgHrzM9PGe","market":"us","size":11509}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-01-27 00:00","pubTimestamp":1643212800,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"14070101","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522016551-CBIO","pdf_url":"","pub_time":1643040000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522016551/0001193125-22-016551-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522016551/d303892dex991.htm","primary":true,"translateUrl":"","linkName":"d303892dex991.htm","type":"EX-99.1","id":"NTFILEHeke7aGQtvJbKS4h","market":"us","size":6972},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522016551/d303892d8k.htm","primary":false,"translateUrl":"","linkName":"d303892d8k.htm","type":"8-K","id":"NTFILE4dfgu5NUgtZMkdn1","market":"us","size":23865},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522016551/g303892g0125064547917.jpg","primary":false,"translateUrl":"","linkName":"g303892g0125064547917.jpg","type":"GRAPHIC","id":"NTFILE2qzZ39zSv7iRSna2","market":"us","size":3353}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-01-25 00:00","pubTimestamp":1643040000,"title_zh":"8-K  - Current report","summary_en":"Item 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13895116","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312522007230-CBIO","pdf_url":"","pub_time":1641916800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"8-K  - Current report","symbol":"CBIO","title":"8-K  - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/0001193125-22-007230-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/d269001dex991.htm","primary":true,"translateUrl":"","linkName":"d269001dex991.htm","type":"EX-99.1","id":"NTFILEKM9qATgZtaExA3DD","market":"us","size":28211},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/d269001d8k.htm","primary":false,"translateUrl":"","linkName":"d269001d8k.htm","type":"8-K","id":"NTFILEEQVMNLkVE1NPXoXx","market":"us","size":25124},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s10g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s10g1.jpg","type":"GRAPHIC","id":"NTFILEABRaq7XvgVVgYpY6","market":"us","size":697259},{"description":"GRAPHIC","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s11g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s11g1.jpg","type":"GRAPHIC","id":"NTFILE8L61manxd1A38P5K","market":"us","size":779890},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s12g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s12g1.jpg","type":"GRAPHIC","id":"NTFILEGNFZjZaoHEMSUpNp","market":"us","size":542469},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s13g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s13g1.jpg","type":"GRAPHIC","id":"NTFILE44D3jDwbD9RLTh3A","market":"us","size":660540},{"description":"GRAPHIC","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s14g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s14g1.jpg","type":"GRAPHIC","id":"NTFILE8yJjDNj9HaLoHhhz","market":"us","size":652343},{"description":"GRAPHIC","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s15g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s15g1.jpg","type":"GRAPHIC","id":"NTFILE9H2x4TQkPueA2ciY","market":"us","size":601250},{"description":"GRAPHIC","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s16g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s16g1.jpg","type":"GRAPHIC","id":"NTFILEee61wWamRydczcJg","market":"us","size":616840},{"description":"GRAPHIC","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s17g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s17g1.jpg","type":"GRAPHIC","id":"NTFILEHcSADNXfYSGLcXqr","market":"us","size":449188},{"description":"GRAPHIC","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s18g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s18g1.jpg","type":"GRAPHIC","id":"NTFILE7tRQ8RmjZZGxcK52","market":"us","size":646981},{"description":"GRAPHIC","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s19g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s19g1.jpg","type":"GRAPHIC","id":"NTFILE9UqFvnVaQzT9GTbo","market":"us","size":639063},{"description":"GRAPHIC","seq":16,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s1g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s1g1.jpg","type":"GRAPHIC","id":"NTFILE7eHCexDhZ5isGbu1","market":"us","size":251930},{"description":"GRAPHIC","seq":17,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s20g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s20g1.jpg","type":"GRAPHIC","id":"NTFILEAt5PuFxzqirWAygj","market":"us","size":510781},{"description":"GRAPHIC","seq":18,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s21g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s21g1.jpg","type":"GRAPHIC","id":"NTFILE8CnR3NPcsB79tQyQ","market":"us","size":374547},{"description":"GRAPHIC","seq":19,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s22g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s22g1.jpg","type":"GRAPHIC","id":"NTFILEEhohBioV7j851wD6","market":"us","size":563617},{"description":"GRAPHIC","seq":20,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s23g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s23g1.jpg","type":"GRAPHIC","id":"NTFILEDo6aaFsUrnE1dMBi","market":"us","size":613276},{"description":"GRAPHIC","seq":21,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s24g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s24g1.jpg","type":"GRAPHIC","id":"NTFILE5e4Uznyz1mZmdwy8","market":"us","size":620010},{"description":"GRAPHIC","seq":22,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s25g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s25g1.jpg","type":"GRAPHIC","id":"NTFILEDDv88zuvg3az7T9m","market":"us","size":566488},{"description":"GRAPHIC","seq":23,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s26g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s26g1.jpg","type":"GRAPHIC","id":"NTFILE8Me9ADwUSQxoTrqa","market":"us","size":509646},{"description":"GRAPHIC","seq":24,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s27g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s27g1.jpg","type":"GRAPHIC","id":"NTFILE9T62TusKv6614yD5","market":"us","size":540343},{"description":"GRAPHIC","seq":25,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s28g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s28g1.jpg","type":"GRAPHIC","id":"NTFILEBHsTSkaNCdL2fEAS","market":"us","size":425289},{"description":"GRAPHIC","seq":26,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s29g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s29g1.jpg","type":"GRAPHIC","id":"NTFILEGDVroyWdP4yHMf1Z","market":"us","size":663206},{"description":"GRAPHIC","seq":27,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s2g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s2g1.jpg","type":"GRAPHIC","id":"NTFILE5xdDiwdy4iTT9jEs","market":"us","size":920827},{"description":"GRAPHIC","seq":28,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s30g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s30g1.jpg","type":"GRAPHIC","id":"NTFILEFExM2ujqPxq4oEUF","market":"us","size":325796},{"description":"GRAPHIC","seq":29,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s31g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s31g1.jpg","type":"GRAPHIC","id":"NTFILE41GyoTHKLL3qCyv4","market":"us","size":198174},{"description":"GRAPHIC","seq":30,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s3g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s3g1.jpg","type":"GRAPHIC","id":"NTFILEASMDBjNjuHSpUTvY","market":"us","size":987449},{"description":"GRAPHIC","seq":31,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s4g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s4g1.jpg","type":"GRAPHIC","id":"NTFILE9LzPii6JxSzWTmpt","market":"us","size":578009},{"description":"GRAPHIC","seq":32,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s5g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s5g1.jpg","type":"GRAPHIC","id":"NTFILEHCWZMeM9HN6MscBa","market":"us","size":541365},{"description":"GRAPHIC","seq":33,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s6g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s6g1.jpg","type":"GRAPHIC","id":"NTFILEhkZYDkZd8CFp4phq","market":"us","size":608771},{"description":"GRAPHIC","seq":34,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s7g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s7g1.jpg","type":"GRAPHIC","id":"NTFILE7LQpxB84gETJiSaD","market":"us","size":602794},{"description":"GRAPHIC","seq":35,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s8g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s8g1.jpg","type":"GRAPHIC","id":"NTFILE4m4q5o9dN8vU83wh","market":"us","size":638241},{"description":"GRAPHIC","seq":36,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000119312522007230/g269001ex99_1s9g1.jpg","primary":false,"translateUrl":"","linkName":"g269001ex99_1s9g1.jpg","type":"GRAPHIC","id":"NTFILE4cMN4B1Jb9z2JWDC","market":"us","size":687793}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2022-01-12 00:00","pubTimestamp":1641916800,"title_zh":"8-K  - Current report","summary_en":"Item 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13812851","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465922001583-CBIO","pdf_url":"","pub_time":1641312000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","symbol":"CBIO","title":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922001583/0001104659-22-001583-index.htm","us_notice_code":"Form SC 13D/A","us_title_en":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SCHEDULE 13D/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000110465922001583/tm221935d1_sc13da.htm","primary":true,"translateUrl":"","linkName":"tm221935d1_sc13da.htm","type":"SC 13D/A","id":"NTFILE6JYVdEjBhnD1kcRH","market":"us","size":147965}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2022-01-05 00:00","pubTimestamp":1641312000,"title_zh":"SC 13D/A [Amend]  - General statement of acquisition of beneficial ownership","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13583095","market":"us","labels":[],"media":"sec.gov","original_id":"AN120919121061260-CBIO","pdf_url":"","pub_time":1634745600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"3  - Initial statement of beneficial ownership of securities","symbol":"CBIO","title":"3  - Initial statement of beneficial ownership of securities","titleType":"Statement Of Changes In Beneficial Ownership","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1124105/000120919121061260/0001209191-21-061260-index.htm","us_notice_code":"Form 3","us_title_en":"3  - Initial statement of beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 3 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000120919121061260/xslF345X02/doc3.xml","primary":true,"translateUrl":"","linkName":"doc3.html","type":"3","id":"NTFILEAy4b4jNWUAs4exEE","market":"us","size":0}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Statement Of Changes In Beneficial Ownership","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Statement Of Changes In Beneficial Ownership","pubTime":"2021-10-21 00:00","pubTimestamp":1634745600,"title_zh":"3  - Initial statement of beneficial ownership of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13583101","market":"us","labels":[],"media":"sec.gov","original_id":"AN120919121059429-CBIO","pdf_url":"","pub_time":1633363200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"4  - Statement of changes in beneficial ownership of securities","symbol":"CBIO","title":"4  - Statement of changes in beneficial ownership of securities","titleType":"Statement Of Changes In Beneficial Ownership","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1124105/000120919121059429/0001209191-21-059429-index.htm","us_notice_code":"Form 4","us_title_en":"4  - Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1124105/000120919121059429/xslF345X03/doc4.xml","primary":true,"translateUrl":"","linkName":"doc4.html","type":"4","id":"NTFILEHuPhgzXexXJiAXLu","market":"us","size":0}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Statement Of Changes In Beneficial Ownership","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Statement Of Changes In Beneficial Ownership","pubTime":"2021-10-05 00:00","pubTimestamp":1633363200,"title_zh":"4  - Statement of changes in beneficial ownership of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0}],"pageSize":20,"totalPage":14,"pageCount":6,"totalSize":270,"code":"91000000","status":"200"}]}}