US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

Ionis Pharmaceuticals

51.44

-2.7700-5.11%

Post-market: 51.600.1600+0.31%19:30 EDT

Volume:5.97M

Turnover:312.34M

Market Cap:8.55B

PE:-14.78

High:55.50

Open:54.88

Low:51.31

Close:54.21

52wk High:86.74

52wk Low:50.01

Shares:166.18M

Float Shares:161.92M

Volume Ratio:1.48

T/O Rate:3.69%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.4800

EPS(LYR):-2.3812

ROE:-105.50%

ROA:-12.42%

PB:19.44

PE(LYR):-21.60

Loading ...

Overview Company News Filings

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Annual Report

Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]

Major Issues Report

Form 8-K - Current report

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

Proposed Sale Of Securities

Form 144 - Report of proposed sale of securities

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers HK | Online Trading in stocks, bonds & ETFS","description":"Discover Tiger Brokers HK, an online trading platform for stocks&ETFs, options&futures, bonds and crypto. Open an account to enjoy low commission trading today!","keywords":"tiger trading,tiger security,tiger broker hk,tigers co ltd,tiger trade hk,tiger brokers hk,stock broker,securities broker,online brokerage,hong kong broker,hk broker,online stock trading,online trading platform,stock trading platforms,trading application,stock trading,stock trading hong kong,buying stocks in hong kong,tiger brokers","social":{"ogDescription":"Discover Tiger Brokers HK, an online trading platform for stocks&ETFs, options&futures, bonds and crypto. Open an account to enjoy low commission trading today!","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.imtigers.com/stock/IONS/filings?page=3"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"HKG","license":"TBHK","edition":"fundamental","symbol":"IONS","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"IONS\",,,,,undefined,":{"symbol":"IONS","market":"US","secType":"STK","nameCN":"Ionis Pharmaceuticals","latestPrice":51.44,"timestamp":1789416000000,"preClose":54.21,"halted":0,"volume":5974753,"hourTrading":{"tag":"盘后","latestPrice":51.6,"preClose":51.44,"latestTime":"19:30 EDT","volume":498283,"amount":25645077.346436,"timestamp":1789428602513,"change":0.16,"changeRate":0.00311,"amplitude":0.011514},"delay":0,"changeRate":-0.05109758347168425,"floatShares":161921007,"shares":166184322,"eps":-3.48,"marketStatus":"Post-Mkt","change":-2.77,"latestTime":"09-14 19:44:54 EDT","open":54.88,"high":55.5,"low":51.31,"amount":312340453.801642,"amplitude":0.077292,"askPrice":51.77,"askSize":1,"bidPrice":51.29,"bidSize":25,"shortable":3,"etf":0,"ttmEps":-3.48,"tradingStatus":3,"nextMarketStatus":{"tag":"Closed","tradingStatus":0,"beginTime":1789430400000},"marketStatusCode":4,"adr":0,"adrRate":0,"exchange":"NASDAQ","adjPreClose":54.21,"preHourTrading":{"tag":"盘前","latestPrice":54.63,"preClose":54.21,"latestTime":"09:28 EDT","volume":991,"amount":53546.296689999996,"timestamp":1789392480163,"change":0.42,"changeRate":0.007748,"amplitude":0.023981},"postHourTrading":{"tag":"盘后","latestPrice":51.6,"preClose":51.44,"latestTime":"19:30 EDT","volume":498283,"amount":25645077.346436,"timestamp":1789428602513,"change":0.16,"changeRate":0.00311,"amplitude":0.011514},"volumeRatio":1.484951,"impliedVol":0.4436,"impliedVolPercentile":0.4821},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"IONS\",,,,,undefined,":{"symbol":"IONS","floatShares":161921007,"roa":"-12.42%","roe":"-105.50%","lyrEps":-2.38125,"volumeRatio":1.484951,"shares":166184322,"dividePrice":0,"high":55.5,"amplitude":0.077292,"preClose":54.21,"low":51.31,"week52Low":50.005,"pbRate":"19.44","psRate":"9.78","week52High":86.74,"institutionHeld":0.92,"latestPrice":51.44,"committee":0.923077,"eps":-3.48,"divideRate":0,"volume":5974753,"delay":0,"ttmEps":-3.48,"open":54.88,"prevYearClose":79.11,"prevWeekClose":54.21,"prevMonthClose":60.36,"prevQuarterClose":79.29,"fiveDayClose":58.09,"twentyDayClose":57.24,"sixtyDayClose":74.31},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/IONS\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-07-29","symbol":"IONS","fiscalQuarterEnding":"2026/06","expectedEps":-1.09,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1785297600000,"reportTimeType":"pre","actualEps":-0.7},{"market":"US","date":"2026-04-29","symbol":"IONS","fiscalQuarterEnding":"2026/03","expectedEps":-0.89,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1777435200000,"reportTimeType":"pre","actualEps":-0.56},{"market":"US","date":"2026-02-25","symbol":"IONS","fiscalQuarterEnding":"2025/12","expectedEps":-1.31,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1771995600000,"reportTimeType":"pre","actualEps":-1.41},{"market":"US","date":"2025-10-29","symbol":"IONS","fiscalQuarterEnding":"2025/09","expectedEps":-1.23,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1761710400000,"reportTimeType":"pre","actualEps":-0.8},{"market":"US","date":"2025-07-30","symbol":"IONS","fiscalQuarterEnding":"2025/06","expectedEps":-0.11,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1753848000000,"reportTimeType":"pre","actualEps":0.7}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"IONS\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"IONS\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.2308,"buy":0.5385,"hold":0.2308,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.5385,"analysts":26,"updateTime":1787284800000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/IONS\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"IONS","date":"2026-09-11","current":-14.781609,"percent":0.658259,"low":-1664.931905,"twenty":-46.83029,"median":-17.982683,"eighty":-11.688179,"high":882.260453,"avg":-65.173123,"sd":366.235058,"marketCap":9248157519},"quantilePoints":[{"date":"2021-09-17","current":-9.553748,"twenty":-43.823694,"median":22.105712,"eighty":90.484478,"marketCap":5252105842},{"date":"2021-09-24","current":-9.294428,"twenty":-43.823694,"median":21.894477,"eighty":89.822908,"marketCap":5109546667},{"date":"2021-10-01","current":-8.61917,"twenty":-43.823694,"median":21.739571,"eighty":88.160122,"marketCap":4738328221},{"date":"2021-10-08","current":-8.752681,"twenty":-43.823694,"median":21.475528,"eighty":87.371554,"marketCap":4811725024},{"date":"2021-10-15","current":-9.012001,"twenty":-43.823694,"median":21.145012,"eighty":86.264015,"marketCap":4954284199},{"date":"2021-10-22","current":-7.815535,"twenty":-43.823694,"median":21.004285,"eighty":84.663252,"marketCap":4296535927},{"date":"2021-10-29","current":-8.182691,"twenty":-43.823694,"median":20.82218,"eighty":83.19244,"marketCap":4498377135},{"date":"2021-11-05","current":-7.827936,"twenty":-43.823694,"median":20.669316,"eighty":82.070133,"marketCap":4757365405},{"date":"2021-11-12","current":-7.595584,"twenty":-43.823694,"median":20.616507,"eighty":76.079084,"marketCap":4616155390},{"date":"2021-11-19","current":-7.432938,"twenty":-43.823694,"median":20.366546,"eighty":75.49578,"marketCap":4517308379},{"date":"2021-11-26","current":-6.749823,"twenty":-43.823694,"median":20.294106,"eighty":74.547727,"marketCap":4102150935},{"date":"2021-12-03","current":-6.131767,"twenty":-43.823694,"median":20.173015,"eighty":74.030875,"marketCap":3726532295},{"date":"2021-12-10","current":-6.847411,"twenty":-43.823694,"median":20.114106,"eighty":72.607318,"marketCap":4161459142},{"date":"2021-12-17","current":-7.542143,"twenty":-43.823694,"median":20.025743,"eighty":70.436541,"marketCap":4583677086},{"date":"2021-12-23","current":-7.600231,"twenty":-43.823694,"median":19.891562,"eighty":60.214071,"marketCap":4618979590},{"date":"2021-12-31","current":-7.070469,"twenty":-43.823694,"median":19.796653,"eighty":53.012098,"marketCap":4297020756},{"date":"2022-01-07","current":-7.058851,"twenty":-43.611673,"median":19.749198,"eighty":51.923862,"marketCap":4289960255},{"date":"2022-01-14","current":-7.686201,"twenty":-43.611673,"median":19.64938,"eighty":51.147099,"marketCap":4671227296},{"date":"2022-01-21","current":-6.942675,"twenty":-43.611673,"median":19.61175,"eighty":50.934296,"marketCap":4219355248},{"date":"2022-01-28","current":-7.360909,"twenty":-43.611673,"median":19.468798,"eighty":50.847883,"marketCap":4473533275},{"date":"2022-02-04","current":-7.319085,"twenty":-43.611673,"median":19.28882,"eighty":50.5876,"marketCap":4448115472},{"date":"2022-02-11","current":-7.639731,"twenty":-43.611673,"median":19.164904,"eighty":50.143461,"marketCap":4642985293},{"date":"2022-02-18","current":-7.497996,"twenty":-43.611673,"median":18.965356,"eighty":49.908881,"marketCap":4556847184},{"date":"2022-02-25","current":-157.459445,"twenty":-44.533501,"median":18.77393,"eighty":49.713145,"marketCap":4502867744},{"date":"2022-03-04","current":-160.035874,"twenty":-45.829592,"median":18.155386,"eighty":49.32903,"marketCap":4576545882},{"date":"2022-03-11","current":-159.49086,"twenty":-46.633425,"median":-6.144547,"eighty":48.69515,"marketCap":4560960122},{"date":"2022-03-18","current":-174.652153,"twenty":-47.12015,"median":-6.881102,"eighty":48.427938,"marketCap":4994527626},{"date":"2022-03-25","current":-181.687786,"twenty":-47.927671,"median":-7.000763,"eighty":48.265452,"marketCap":5195725619},{"date":"2022-04-01","current":-192.736702,"twenty":-48.230031,"median":-7.040263,"eighty":47.833218,"marketCap":5511691480},{"date":"2022-04-08","current":-198.781401,"twenty":-48.689101,"median":-7.082087,"eighty":47.228668,"marketCap":5684551727},{"date":"2022-04-14","current":-202.992871,"twenty":-49.716018,"median":-7.119262,"eighty":46.918857,"marketCap":5804987145},{"date":"2022-04-22","current":-206.852389,"twenty":-50.435043,"median":-7.237762,"eighty":46.570634,"marketCap":5915357781},{"date":"2022-04-29","current":-182.216483,"twenty":-51.591015,"median":-7.300497,"eighty":46.245658,"marketCap":5210844764},{"date":"2022-05-06","current":-1322.183946,"twenty":-128.214398,"median":-7.341159,"eighty":45.925265,"marketCap":5147262100},{"date":"2022-05-13","current":-1314.170709,"twenty":-130.326929,"median":-7.37485,"eighty":45.90793,"marketCap":5116066572},{"date":"2022-05-20","current":-1438.375868,"twenty":-130.86667,"median":-7.37485,"eighty":45.90793,"marketCap":5599597254},{"date":"2022-05-27","current":-1370.6276,"twenty":-132.625178,"median":-7.37485,"eighty":45.90793,"marketCap":5335853246},{"date":"2022-06-03","current":-1316.720376,"twenty":-134.128325,"median":-7.37485,"eighty":45.90793,"marketCap":5125992422},{"date":"2022-06-10","current":-1266.091293,"twenty":-137.45382,"median":-7.37485,"eighty":45.90793,"marketCap":4928893405},{"date":"2022-06-17","current":-1284.303193,"twenty":-139.005646,"median":-7.37485,"eighty":45.90793,"marketCap":4999792332},{"date":"2022-06-24","current":-1429.634156,"twenty":-139.862338,"median":-7.360909,"eighty":45.909339,"marketCap":5565565769},{"date":"2022-07-01","current":-1386.289834,"twenty":-141.353878,"median":-7.360909,"eighty":45.909339,"marketCap":5396826323},{"date":"2022-07-08","current":-1353.144176,"twenty":-142.456573,"median":-7.360909,"eighty":45.909339,"marketCap":5267790276},{"date":"2022-07-15","current":-1431.819584,"twenty":-143.808127,"median":-7.360909,"eighty":45.909339,"marketCap":5574073640},{"date":"2022-07-22","current":-1387.746786,"twenty":-144.656772,"median":-7.360909,"eighty":45.909339,"marketCap":5402498237},{"date":"2022-07-29","current":-1368.077934,"twenty":-146.022974,"median":-7.360909,"eighty":45.909339,"marketCap":5325927396},{"date":"2022-08-05","current":-1664.567667,"twenty":-147.819198,"median":-7.360909,"eighty":45.909339,"marketCap":6480161927},{"date":"2022-08-12","current":-222.342663,"twenty":-148.698169,"median":-7.360909,"eighty":45.909339,"marketCap":6259613005},{"date":"2022-08-19","current":-221.838485,"twenty":-149.407406,"median":-7.360909,"eighty":45.909339,"marketCap":6245418872},{"date":"2022-08-26","current":-213.519542,"twenty":-149.883165,"median":-7.360909,"eighty":45.909339,"marketCap":6011215664},{"date":"2022-09-02","current":-218.006729,"twenty":-150.165357,"median":-7.360909,"eighty":45.909339,"marketCap":6137543455},{"date":"2022-09-09","current":-236.157151,"twenty":-151.092649,"median":-7.360909,"eighty":45.909339,"marketCap":6648532271},{"date":"2022-09-16","current":-233.585841,"twenty":-153.529951,"median":-7.360909,"eighty":45.909339,"marketCap":6576142189},{"date":"2022-09-23","current":-217.956312,"twenty":-156.46647,"median":-7.360909,"eighty":45.909339,"marketCap":6136124041},{"date":"2022-09-30","current":-222.998095,"twenty":-157.969129,"median":-7.360909,"eighty":45.909339,"marketCap":6278065379},{"date":"2022-10-07","current":-231.569128,"twenty":-159.577078,"median":-7.360909,"eighty":45.909339,"marketCap":6519365654},{"date":"2022-10-14","current":-233.737095,"twenty":-160.082841,"median":-7.360909,"eighty":45.909339,"marketCap":6580400429},{"date":"2022-10-21","current":-226.62818,"twenty":-160.43291,"median":-7.360909,"eighty":45.909339,"marketCap":6380263143},{"date":"2022-10-28","current":-224.913973,"twenty":-161.94987,"median":-7.360909,"eighty":45.909339,"marketCap":6332003088},{"date":"2022-11-04","current":-209.486115,"twenty":-162.370971,"median":-7.360909,"eighty":45.909339,"marketCap":5897662593},{"date":"2022-11-11","current":839.185498,"twenty":-162.756411,"median":-7.319085,"eighty":46.031035,"marketCap":6143677032},{"date":"2022-11-18","current":836.080997,"twenty":-162.756411,"median":-7.284232,"eighty":46.34415,"marketCap":6120948978},{"date":"2022-11-25","current":806.394204,"twenty":-162.756411,"median":-7.219174,"eighty":46.64061,"marketCap":5903611964},{"date":"2022-12-02","current":782.334319,"twenty":-162.756411,"median":-7.102998,"eighty":47.141347,"marketCap":5727469547},{"date":"2022-12-09","current":727.617484,"twenty":-162.756411,"median":-7.058851,"eighty":47.387939,"marketCap":5326887600},{"date":"2022-12-16","current":750.125118,"twenty":-162.756411,"median":-7.014704,"eighty":48.047842,"marketCap":5491665989},{"date":"2022-12-23","current":740.423552,"twenty":-162.756411,"median":-6.972881,"eighty":48.293594,"marketCap":5420640821},{"date":"2022-12-30","current":732.85633,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5365241190},{"date":"2023-01-06","current":786.214945,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5755879614},{"date":"2023-01-13","current":773.214846,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5660705889},{"date":"2023-01-20","current":790.871697,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5789971695},{"date":"2023-01-27","current":776.513379,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5684854446},{"date":"2023-02-03","current":793.976198,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5812699749},{"date":"2023-02-10","current":756.722183,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5539963104},{"date":"2023-02-17","current":748.96093,"twenty":-162.756411,"median":-6.749823,"eighty":48.503303,"marketCap":5483142969},{"date":"2023-02-24","current":-18.915876,"twenty":-162.756411,"median":-6.942675,"eighty":48.318169,"marketCap":5102028010},{"date":"2023-03-03","current":-19.398181,"twenty":-162.756411,"median":-7.010057,"eighty":48.167441,"marketCap":5232116143},{"date":"2023-03-10","current":-17.998968,"twenty":-162.756411,"median":-7.047233,"eighty":47.522459,"marketCap":4854717602},{"date":"2023-03-17","current":-18.645574,"twenty":-162.756411,"median":-7.096027,"eighty":47.151665,"marketCap":5029121473},{"date":"2023-03-24","current":-17.993668,"twenty":-162.756411,"median":-7.188968,"eighty":46.719576,"marketCap":4853288062},{"date":"2023-03-31","current":-18.942377,"twenty":-162.739653,"median":-7.283071,"eighty":46.447558,"marketCap":5109175709},{"date":"2023-04-06","current":-19.392881,"twenty":-162.739653,"median":-7.309791,"eighty":46.139197,"marketCap":5230686603},{"date":"2023-04-14","current":-19.906986,"twenty":-162.756411,"median":-7.388791,"eighty":45.881909,"marketCap":5369351977},{"date":"2023-04-21","current":-19.158378,"twenty":-162.756411,"median":-7.484055,"eighty":45.586713,"marketCap":5167435947},{"date":"2023-04-28","current":-18.691747,"twenty":-162.756411,"median":-7.542143,"eighty":45.238708,"marketCap":5041575343},{"date":"2023-05-05","current":-15.654507,"twenty":-162.722895,"median":-7.581643,"eighty":45.096531,"marketCap":5148454369},{"date":"2023-05-12","current":-15.484823,"twenty":-162.005118,"median":-7.581643,"eighty":45.096531,"marketCap":5092648444},{"date":"2023-05-19","current":-15.937315,"twenty":-160.611822,"median":-7.581643,"eighty":45.096531,"marketCap":5241464245},{"date":"2023-05-26","current":-17.042442,"twenty":-160.205418,"median":-7.581643,"eighty":45.096531,"marketCap":5604918222},{"date":"2023-06-02","current":-18.682728,"twenty":-159.773437,"median":-7.581643,"eighty":45.096531,"marketCap":6144375503},{"date":"2023-06-09","current":-18.121463,"twenty":-159.192484,"median":-7.581643,"eighty":45.096531,"marketCap":5959786673},{"date":"2023-06-16","current":-18.138866,"twenty":-156.985977,"median":-7.581643,"eighty":45.096531,"marketCap":5965510357},{"date":"2023-06-23","current":-17.925673,"twenty":-155.435521,"median":-7.578157,"eighty":45.109315,"marketCap":5895395220},{"date":"2023-06-30","current":-17.886515,"twenty":-151.740635,"median":-7.574672,"eighty":45.122099,"marketCap":5882516929},{"date":"2023-07-07","current":-18.169323,"twenty":-150.657265,"median":-7.574672,"eighty":45.122099,"marketCap":5975526805},{"date":"2023-07-14","current":-18.560903,"twenty":-150.083568,"median":-7.574672,"eighty":45.122099,"marketCap":6104309711},{"date":"2023-07-21","current":-17.821251,"twenty":-149.641501,"median":-7.574672,"eighty":45.122099,"marketCap":5861053112},{"date":"2023-07-28","current":-16.750932,"twenty":-149.090615,"median":-7.574672,"eighty":45.122099,"marketCap":5509046504},{"date":"2023-08-04","current":-17.151214,"twenty":-148.303568,"median":-7.574672,"eighty":45.122099,"marketCap":5640691252},{"date":"2023-08-11","current":-18.467972,"twenty":-148.00823,"median":-7.574672,"eighty":45.122099,"marketCap":5707249602},{"date":"2023-08-18","current":-18.147959,"twenty":-147.735407,"median":-7.574672,"eighty":45.122099,"marketCap":5608354519},{"date":"2023-08-25","current":-18.463334,"twenty":-145.579013,"median":-7.574672,"eighty":45.122099,"marketCap":5705816340},{"date":"2023-09-01","current":-18.676675,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":5771746396},{"date":"2023-09-08","current":-18.727692,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":5787512279},{"date":"2023-09-15","current":-20.239635,"twenty":-145.219114,"median":-7.574672,"eighty":45.122099,"marketCap":6254755717},{"date":"2023-09-22","current":-19.701643,"twenty":-144.797122,"median":-7.574672,"eighty":45.122099,"marketCap":6088497315},{"date":"2023-09-29","current":-21.454756,"twenty":-143.400598,"median":-7.574672,"eighty":45.122099,"marketCap":6630270382},{"date":"2023-10-06","current":-21.728389,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6714832844},{"date":"2023-10-13","current":-21.38055,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6607338188},{"date":"2023-10-20","current":-21.593891,"twenty":-143.032342,"median":-7.574672,"eighty":45.122099,"marketCap":6673268244},{"date":"2023-10-27","current":-21.16257,"twenty":-143.300049,"median":-7.55957,"eighty":45.146419,"marketCap":6539974871},{"date":"2023-11-03","current":-15.297336,"twenty":-140.032184,"median":-7.55957,"eighty":45.146419,"marketCap":6267655075},{"date":"2023-11-10","current":-16.577399,"twenty":-22.395314,"median":-7.55957,"eighty":45.146419,"marketCap":6787665949},{"date":"2023-11-17","current":-17.008391,"twenty":-21.672735,"median":-7.55957,"eighty":45.146419,"marketCap":6964136656},{"date":"2023-11-24","current":-17.460406,"twenty":-21.484438,"median":-7.55957,"eighty":45.146419,"marketCap":7149215689},{"date":"2023-12-01","current":-17.334262,"twenty":-21.2275,"median":-7.55957,"eighty":45.146419,"marketCap":7097565726},{"date":"2023-12-08","current":-17.334262,"twenty":-20.411236,"median":-7.572349,"eighty":45.140651,"marketCap":7097565726},{"date":"2023-12-15","current":-17.456902,"twenty":-20.127399,"median":-7.572349,"eighty":45.140651,"marketCap":7147780968},{"date":"2023-12-22","current":-17.208119,"twenty":-19.907658,"median":-7.572349,"eighty":45.140651,"marketCap":7045915764},{"date":"2023-12-29","current":-17.695174,"twenty":-19.76602,"median":-7.55957,"eighty":45.146419,"marketCap":7245342009},{"date":"2024-01-05","current":-18.038565,"twenty":-19.665059,"median":-7.54679,"eighty":45.152187,"marketCap":7385944686},{"date":"2024-01-12","current":-18.763892,"twenty":-19.458602,"median":-7.54679,"eighty":45.152187,"marketCap":7682931972},{"date":"2024-01-19","current":-17.747734,"twenty":-19.2678,"median":-7.544467,"eighty":45.157955,"marketCap":7266862827},{"date":"2024-01-26","current":-18.073605,"twenty":-19.134896,"median":-7.54679,"eighty":45.152187,"marketCap":7400291898},{"date":"2024-02-02","current":-17.859862,"twenty":-19.007278,"median":-7.54679,"eighty":45.152187,"marketCap":7312773905},{"date":"2024-02-09","current":-17.512966,"twenty":-18.941814,"median":-7.54679,"eighty":45.152187,"marketCap":7170736507},{"date":"2024-02-16","current":-15.866089,"twenty":-18.881956,"median":-7.54679,"eighty":45.152187,"marketCap":6496417548},{"date":"2024-02-23","current":-17.500434,"twenty":-18.811317,"median":-7.54679,"eighty":45.152187,"marketCap":6410164032},{"date":"2024-03-01","current":-17.989873,"twenty":-18.791838,"median":-7.578157,"eighty":45.146419,"marketCap":6589438742},{"date":"2024-03-08","current":-17.774998,"twenty":-18.791838,"median":-7.603716,"eighty":45.146419,"marketCap":6510732771},{"date":"2024-03-15","current":-16.784182,"twenty":-18.791838,"median":-7.673842,"eighty":45.146419,"marketCap":6147810797},{"date":"2024-03-22","current":-17.010995,"twenty":-18.791838,"median":-7.777023,"eighty":45.146419,"marketCap":6230889321},{"date":"2024-03-28","current":-17.771018,"twenty":-18.791838,"median":-7.81825,"eighty":45.146419,"marketCap":6509275254},{"date":"2024-04-05","current":-17.042828,"twenty":-18.796083,"median":-7.904612,"eighty":45.152187,"marketCap":6242549465},{"date":"2024-04-12","current":-16.911516,"twenty":-18.796083,"median":-8.182691,"eighty":45.152187,"marketCap":6194451372},{"date":"2024-04-19","current":-16.239034,"twenty":-18.796083,"median":-8.560117,"eighty":45.152187,"marketCap":5948130835},{"date":"2024-04-26","current":-16.659633,"twenty":-18.791838,"median":-8.646128,"eighty":45.146419,"marketCap":6102190447},{"date":"2024-05-03","current":-17.157352,"twenty":-18.791838,"median":-8.845112,"eighty":45.146419,"marketCap":6284497762},{"date":"2024-05-10","current":-14.961134,"twenty":-18.791838,"median":-9.293144,"eighty":45.146419,"marketCap":5756535778},{"date":"2024-05-17","current":-14.25989,"twenty":-18.791838,"median":-9.334225,"eighty":45.146419,"marketCap":5486720952},{"date":"2024-05-24","current":-14.40393,"twenty":-18.791838,"median":-9.552464,"eighty":45.146419,"marketCap":5542142376},{"date":"2024-05-31","current":-13.854306,"twenty":-18.791838,"median":-9.739892,"eighty":45.146419,"marketCap":5330665890},{"date":"2024-06-07","current":-15.112755,"twenty":-18.791838,"median":-9.90935,"eighty":45.146419,"marketCap":5814874119},{"date":"2024-06-14","current":-15.586568,"twenty":-18.796083,"median":-9.987659,"eighty":45.152187,"marketCap":5997181434},{"date":"2024-06-21","current":-15.469062,"twenty":-18.800329,"median":-10.068299,"eighty":45.157955,"marketCap":5951969220},{"date":"2024-06-28","current":-17.902568,"twenty":-18.809069,"median":-10.099656,"eighty":45.171414,"marketCap":6888299589},{"date":"2024-07-05","current":-17.284716,"twenty":-18.809069,"median":-10.146845,"eighty":45.171414,"marketCap":6650570851},{"date":"2024-07-12","current":-17.932892,"twenty":-18.809069,"median":-10.187925,"eighty":45.171414,"marketCap":6899967258},{"date":"2024-07-15","current":-18.194437,"twenty":-18.809069,"median":-10.208466,"eighty":45.171414,"marketCap":7000600896},{"date":"2024-08-02","current":-20.490271,"twenty":-18.868176,"median":-10.389456,"eighty":45.307924,"marketCap":7484809124},{"date":"2024-08-09","current":-18.992918,"twenty":-18.884076,"median":-10.451704,"eighty":45.307924,"marketCap":6946488933},{"date":"2024-08-16","current":-18.655115,"twenty":-18.884076,"median":-10.488762,"eighty":45.307924,"marketCap":6822940561},{"date":"2024-08-23","current":-19.004911,"twenty":-18.92096,"median":-10.554325,"eighty":45.307924,"marketCap":6950875266},{"date":"2024-08-30","current":-19.948361,"twenty":-18.942377,"median":-10.636992,"eighty":45.307924,"marketCap":7295933440},{"date":"2024-09-06","current":-19.248769,"twenty":-18.979477,"median":-10.675476,"eighty":45.307924,"marketCap":7040064031},{"date":"2024-09-13","current":-17.667381,"twenty":-18.992918,"median":-10.762419,"eighty":45.307924,"marketCap":6461685590},{"date":"2024-09-20","current":-18.408188,"twenty":-18.992918,"median":-10.826557,"eighty":45.307924,"marketCap":6732629014},{"date":"2024-09-27","current":-17.701837,"twenty":-18.992918,"median":-11.068858,"eighty":45.307924,"marketCap":6474287610},{"date":"2024-10-04","current":-16.284829,"twenty":-18.992918,"median":-11.242743,"eighty":45.307924,"marketCap":5956029551},{"date":"2024-10-11","current":-16.345127,"twenty":-18.992918,"median":-12.040191,"eighty":45.307924,"marketCap":5978083085},{"date":"2024-10-18","current":-16.577706,"twenty":-18.992918,"median":-13.03948,"eighty":45.307924,"marketCap":6063146718},{"date":"2024-10-25","current":-16.698302,"twenty":-18.992918,"median":-13.446915,"eighty":45.307924,"marketCap":6107253787},{"date":"2024-10-31","current":-16.909346,"twenty":-18.992918,"median":-13.562755,"eighty":45.307924,"marketCap":6184441157},{"date":"2024-11-08","current":-16.902216,"twenty":-18.995317,"median":-13.748329,"eighty":45.31946,"marketCap":6072729658},{"date":"2024-11-15","current":-16.383322,"twenty":-18.995317,"median":-13.840323,"eighty":45.31946,"marketCap":5878515995},{"date":"2024-11-22","current":-14.935534,"twenty":-18.995317,"median":-14.176174,"eighty":45.31946,"marketCap":5359033920},{"date":"2024-11-29","current":-15.723236,"twenty":-18.995317,"median":-14.25989,"eighty":45.31946,"marketCap":5641670064},{"date":"2024-12-06","current":-16.172094,"twenty":-18.995317,"median":-14.506273,"eighty":45.31946,"marketCap":5802725297},{"date":"2024-12-13","current":-16.286509,"twenty":-18.995317,"median":-14.813304,"eighty":45.31946,"marketCap":5843778591},{"date":"2024-12-20","current":-15.661628,"twenty":-18.995317,"median":-14.935534,"eighty":45.31946,"marketCap":5619564444},{"date":"2024-12-27","current":-15.98727,"twenty":-18.995317,"median":-15.08243,"eighty":45.31946,"marketCap":5736408436},{"date":"2025-01-03","current":-15.265577,"twenty":-18.995317,"median":-15.112755,"eighty":45.31946,"marketCap":5477456886},{"date":"2025-01-10","current":-15.005943,"twenty":-18.997715,"median":-15.244128,"eighty":45.330996,"marketCap":5384297486},{"date":"2025-01-17","current":-14.205039,"twenty":-18.997715,"median":-15.281457,"eighty":45.330996,"marketCap":5096924424},{"date":"2025-01-24","current":-15.164364,"twenty":-18.997715,"median":-15.281457,"eighty":45.330996,"marketCap":5441140510},{"date":"2025-01-31","current":-14.662699,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5261137602},{"date":"2025-02-07","current":-14.359059,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5152188474},{"date":"2025-02-14","current":-13.35573,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4792182660},{"date":"2025-02-21","current":-11.446164,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":5196558396},{"date":"2025-02-28","current":-10.979464,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4983545602},{"date":"2025-03-07","current":-12.044139,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5466798509},{"date":"2025-03-14","current":-11.522308,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5229940998},{"date":"2025-03-21","current":-11.46277,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5202916987},{"date":"2025-03-28","current":-11.109046,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5042362567},{"date":"2025-04-04","current":-9.988335,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":4533675297},{"date":"2025-04-11","current":-9.354433,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4245949060},{"date":"2025-04-17","current":-9.928797,"twenty":-18.997715,"median":-15.294658,"eighty":45.330996,"marketCap":4506651286},{"date":"2025-04-25","current":-10.356068,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":4700588308},{"date":"2025-05-02","current":-11.018739,"twenty":-19.000114,"median":-15.297336,"eighty":45.342533,"marketCap":5046935029},{"date":"2025-05-09","current":-11.380123,"twenty":-19.000114,"median":-15.297336,"eighty":45.26178,"marketCap":5212460492},{"date":"2025-05-16","current":-11.463519,"twenty":-19.000114,"median":-15.297336,"eighty":45.175259,"marketCap":5250658676},{"date":"2025-05-23","current":-11.55734,"twenty":-19.000114,"median":-15.297336,"eighty":45.175259,"marketCap":5293631632},{"date":"2025-05-30","current":-11.626837,"twenty":-19.000114,"median":-15.297336,"eighty":45.007986,"marketCap":5325463452},{"date":"2025-06-06","current":-12.24536,"twenty":-19.000114,"median":-15.297336,"eighty":44.117786,"marketCap":5608766648},{"date":"2025-06-13","current":-12.377404,"twenty":-19.000114,"median":-15.297336,"eighty":-6.098308,"marketCap":5669247106},{"date":"2025-06-20","current":-12.860408,"twenty":-19.002512,"median":-15.301886,"eighty":-6.769341,"marketCap":5890478253},{"date":"2025-06-27","current":-13.82294,"twenty":-19.002512,"median":-15.301886,"eighty":-6.989146,"marketCap":6331348958},{"date":"2025-07-03","current":-14.941841,"twenty":-19.002512,"median":-15.301886,"eighty":-7.017492,"marketCap":6843841257},{"date":"2025-07-11","current":-14.7264,"twenty":-19.002512,"median":-15.301886,"eighty":-7.061175,"marketCap":6745162615},{"date":"2025-07-18","current":-14.653429,"twenty":-19.002512,"median":-15.301886,"eighty":-7.105786,"marketCap":6711739204},{"date":"2025-07-25","current":-14.646479,"twenty":-19.002512,"median":-15.301886,"eighty":-7.221033,"marketCap":6708556022},{"date":"2025-08-01","current":-25.541485,"twenty":-19.026904,"median":-15.342587,"eighty":-7.288415,"marketCap":6850635022},{"date":"2025-08-08","current":-24.394555,"twenty":-19.059439,"median":-15.406519,"eighty":-7.31955,"marketCap":6543009950},{"date":"2025-08-15","current":-25.464231,"twenty":-19.208439,"median":-15.476942,"eighty":-7.439444,"marketCap":6829914162},{"date":"2025-08-22","current":-25.693023,"twenty":-19.327123,"median":-15.573133,"eighty":-7.500784,"marketCap":6891279785},{"date":"2025-08-29","current":-25.32755,"twenty":-19.462842,"median":-15.656683,"eighty":-7.572814,"marketCap":6793254179},{"date":"2025-09-05","current":-35.269594,"twenty":-19.610183,"median":-15.723236,"eighty":-7.595584,"marketCap":9459869441},{"date":"2025-09-12","current":-38.056694,"twenty":-19.731561,"median":-15.763036,"eighty":-7.642541,"marketCap":10207414305},{"date":"2025-09-19","current":-36.689886,"twenty":-19.905803,"median":-15.876073,"eighty":-7.741966,"marketCap":9840814478},{"date":"2025-09-26","current":-37.420831,"twenty":-20.021346,"median":-16.03996,"eighty":-7.801291,"marketCap":10036865690},{"date":"2025-10-03","current":-40.647687,"twenty":-20.250766,"median":-16.203648,"eighty":-7.855354,"marketCap":10902360063},{"date":"2025-10-10","current":-41.758962,"twenty":-20.936243,"median":-16.267488,"eighty":-8.057965,"marketCap":11200421661},{"date":"2025-10-17","current":-43.422902,"twenty":-21.44548,"median":-16.302057,"eighty":-8.466659,"marketCap":11646717103},{"date":"2025-10-24","current":-42.489907,"twenty":-21.627284,"median":-16.365719,"eighty":-8.619683,"marketCap":11396472873},{"date":"2025-10-31","current":-46.865674,"twenty":-22.311833,"median":-16.491552,"eighty":-8.824572,"marketCap":12013640728},{"date":"2025-11-07","current":-46.821444,"twenty":-24.565703,"median":-16.551864,"eighty":-9.220997,"marketCap":12002302521},{"date":"2025-11-14","current":-44.129685,"twenty":-25.310911,"median":-16.577552,"eighty":-9.310347,"marketCap":11312291607},{"date":"2025-11-21","current":-46.202213,"twenty":-25.459477,"median":-16.623152,"eighty":-9.406991,"marketCap":11843567616},{"date":"2025-11-28","current":-52.274467,"twenty":-25.606854,"median":-16.659586,"eighty":-9.54788,"marketCap":13400141532},{"date":"2025-12-05","current":-51.693149,"twenty":-25.977676,"median":-16.714478,"eighty":-9.709339,"marketCap":13251125091},{"date":"2025-12-12","current":-50.00606,"twenty":-36.254884,"median":-16.738094,"eighty":-9.817591,"marketCap":12818653462},{"date":"2025-12-19","current":-49.051939,"twenty":-36.458718,"median":-16.773398,"eighty":-9.930898,"marketCap":12574072128},{"date":"2025-12-26","current":-50.960181,"twenty":-37.51116,"median":-16.804783,"eighty":-9.964551,"marketCap":13063234795},{"date":"2026-01-02","current":-49.987104,"twenty":-38.080464,"median":-16.872737,"eighty":-9.994875,"marketCap":12813794230},{"date":"2026-01-09","current":-51.522544,"twenty":-40.33867,"median":-16.913584,"eighty":-10.055281,"marketCap":13207392005},{"date":"2026-01-16","current":-48.786554,"twenty":-41.579494,"median":-16.936559,"eighty":-10.101905,"marketCap":12506042883},{"date":"2026-01-23","current":-51.680511,"twenty":-42.352038,"median":-16.969214,"eighty":-10.147872,"marketCap":13247885603},{"date":"2026-01-30","current":-53.001116,"twenty":-43.304049,"median":-17.016336,"eighty":-10.177655,"marketCap":13586412084},{"date":"2026-02-06","current":-52.748369,"twenty":-43.896106,"median":-17.042828,"eighty":-10.276361,"marketCap":13521622327},{"date":"2026-02-13","current":-51.674193,"twenty":-45.89007,"median":-17.08842,"eighty":-10.365331,"marketCap":13246265859},{"date":"2026-02-20","current":-52.536693,"twenty":-46.437268,"median":-17.113581,"eighty":-10.415699,"marketCap":13467360905},{"date":"2026-02-27","current":-34.265449,"twenty":-46.808807,"median":-17.154283,"eighty":-10.419492,"marketCap":13055136075},{"date":"2026-03-06","current":-32.554417,"twenty":-46.808807,"median":-17.180856,"eighty":-10.419492,"marketCap":12415831546},{"date":"2026-03-13","current":-31.332977,"twenty":-46.808807,"median":-17.209871,"eighty":-10.419492,"marketCap":11949990075},{"date":"2026-03-20","current":-30.891179,"twenty":-46.808807,"median":-17.218631,"eighty":-10.419492,"marketCap":11781494224},{"date":"2026-03-27","current":-32.155933,"twenty":-46.808807,"median":-17.24834,"eighty":-10.419492,"marketCap":12263854896},{"date":"2026-04-02","current":-32.541423,"twenty":-46.808807,"median":-17.287579,"eighty":-10.419492,"marketCap":12410875786},{"date":"2026-04-10","current":-33.104499,"twenty":-46.808807,"median":-17.33251,"eighty":-10.419492,"marketCap":12625625400},{"date":"2026-04-17","current":-32.597731,"twenty":-46.808807,"median":-17.370954,"eighty":-10.419492,"marketCap":12432350747},{"date":"2026-04-24","current":-32.090963,"twenty":-46.808807,"median":-17.417852,"eighty":-10.419492,"marketCap":12239076094},{"date":"2026-05-01","current":-37.78562,"twenty":-46.808807,"median":-17.460406,"eighty":-10.419492,"marketCap":12355028686},{"date":"2026-05-08","current":-38.422456,"twenty":-46.808807,"median":-17.499692,"eighty":-10.425443,"marketCap":12563259507},{"date":"2026-05-15","current":-38.250612,"twenty":-46.808807,"median":-17.54086,"eighty":-10.441583,"marketCap":12507070238},{"date":"2026-05-22","current":-38.301154,"twenty":-46.808807,"median":-17.626193,"eighty":-10.45769,"marketCap":12523596493},{"date":"2026-05-29","current":-39.084564,"twenty":-46.821444,"median":-17.65446,"eighty":-10.515842,"marketCap":12779753455},{"date":"2026-06-05","current":-37.972628,"twenty":-46.808807,"median":-17.690774,"eighty":-10.584827,"marketCap":12416175832},{"date":"2026-06-12","current":-37.31052,"twenty":-46.808807,"median":-17.738974,"eighty":-10.668419,"marketCap":12199681883},{"date":"2026-06-18","current":-37.558179,"twenty":-46.808807,"median":-17.769888,"eighty":-10.69486,"marketCap":12280660536},{"date":"2026-06-26","current":-39.595044,"twenty":-46.821444,"median":-17.818766,"eighty":-10.726786,"marketCap":12946668637},{"date":"2026-07-02","current":-40.024656,"twenty":-46.821444,"median":-17.854581,"eighty":-10.726786,"marketCap":13087141809},{"date":"2026-07-10","current":-32.483705,"twenty":-46.821444,"median":-17.871767,"eighty":-10.726786,"marketCap":10621424474},{"date":"2026-07-17","current":-27.621511,"twenty":-46.821444,"median":-17.880886,"eighty":-10.979464,"marketCap":9031598685},{"date":"2026-07-24","current":-28.23813,"twenty":-46.821444,"median":-17.925673,"eighty":-11.109046,"marketCap":9233219003},{"date":"2026-07-31","current":-15.666504,"twenty":-46.83029,"median":-17.93492,"eighty":-11.257113,"marketCap":8854300676},{"date":"2026-08-07","current":-16.022293,"twenty":-46.83029,"median":-17.93492,"eighty":-11.326236,"marketCap":9055383705},{"date":"2026-08-14","current":-16.42807,"twenty":-46.83029,"median":-17.93492,"eighty":-11.457268,"marketCap":9284718070},{"date":"2026-08-21","current":-17.277849,"twenty":-46.83029,"median":-17.93492,"eighty":-11.52511,"marketCap":9764990760},{"date":"2026-08-28","current":-18.356979,"twenty":-46.83029,"median":-17.973741,"eighty":-11.565738,"marketCap":10374887222},{"date":"2026-09-04","current":-17.092603,"twenty":-46.83029,"median":-17.982683,"eighty":-11.643516,"marketCap":9660294637},{"date":"2026-09-11","current":-16.363381,"twenty":-46.83029,"median":-17.982683,"eighty":-11.688179,"marketCap":9248157519}],"updateTime":1789429494932},"$inf$@#url:\"https://stock-news.skytigris.cn/v3/notice/important/events/list\",params:#symbol:\"IONS\",pageSize:20,pageCount:3,market:\"us\",,,undefined,":[{"items":[{"cdn_pdf":false,"hasAttachments":true,"id":"20793316","market":"us","labels":[],"media":"sec.gov","original_id":"AN197248126000082-IONS","pdf_url":"","pub_time":1772514000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000082/0001972481-26-000082-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000082/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE4Rnxmsz7SSRmeot8","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-03-03 13:00","pubTimestamp":1772514000,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20793229","market":"us","labels":[],"media":"sec.gov","original_id":"AN197248126000080-IONS","pdf_url":"","pub_time":1772514000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000080/0001972481-26-000080-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000080/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE9q5BFwPDJCa7xhPH","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-03-03 13:00","pubTimestamp":1772514000,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20793221","market":"us","labels":[],"media":"sec.gov","original_id":"AN197248126000081-IONS","pdf_url":"","pub_time":1772514000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000081/0001972481-26-000081-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000081/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEBv63YjDGttR7Ej9b","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-03-03 13:00","pubTimestamp":1772514000,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20793189","market":"us","labels":[],"media":"sec.gov","original_id":"AN197248126000077-IONS","pdf_url":"","pub_time":1772514000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000077/0001972481-26-000077-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000077/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEHGWYe3kVvM1jFd3M","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-03-03 13:00","pubTimestamp":1772514000,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20793168","market":"us","labels":[],"media":"sec.gov","original_id":"AN197248126000078-IONS","pdf_url":"","pub_time":1772514000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000078/0001972481-26-000078-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000078/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEJJATXCjevDpkUNKQ","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-03-03 13:00","pubTimestamp":1772514000,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20778578","market":"us","labels":[],"media":"sec.gov","original_id":"AN87401526000115-IONS","pdf_url":"","pub_time":1772082000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]","symbol":"IONS","title":"Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]","titleType":"Annual Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/0000874015-26-000115-index.htm","us_notice_code":"Form 10-K","us_title_en":"Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"IONIS PHARMACEUTICALS, INC. 10-K 12-31-2025","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/form10k.htm","primary":true,"translateUrl":"","linkName":"form10k.htm","type":"10-K","id":"NTFILE4ypHrHKFDRzXT3pR","market":"us","size":2455988},{"description":"EXHIBIT 21.1","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/ex21-1.htm","primary":false,"translateUrl":"","linkName":"ex21-1.htm","type":"EX-21.1","id":"NTFILEGKTmoxuUbmecuzKJ","market":"us","size":2254},{"description":"EXHIBIT 23.1","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/ex23-1.htm","primary":false,"translateUrl":"","linkName":"ex23-1.htm","type":"EX-23.1","id":"NTFILE5QGeBTgtmcxgKUuv","market":"us","size":3375},{"description":"EXHIBIT 31.1","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/ex31-1.htm","primary":false,"translateUrl":"","linkName":"ex31-1.htm","type":"EX-31.1","id":"NTFILE6qspuSY6TmQEiwsm","market":"us","size":9707},{"description":"EXHIBIT 31.2","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/ex31-2.htm","primary":false,"translateUrl":"","linkName":"ex31-2.htm","type":"EX-31.2","id":"NTFILEBFfo9v9Eiv7rLNpm","market":"us","size":9726},{"description":"EXHIBIT 32.1","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/ex32-1.htm","primary":false,"translateUrl":"","linkName":"ex32-1.htm","type":"EX-32.1","id":"NTFILE841tvTbohv6gfYFx","market":"us","size":5719},{"description":"","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/image01.jpg","primary":false,"translateUrl":"","linkName":"image01.jpg","type":"GRAPHIC","id":"NTFILEGbf4mKV7CNT8PpgW","market":"us","size":25493},{"description":"","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/image02.jpg","primary":false,"translateUrl":"","linkName":"image02.jpg","type":"GRAPHIC","id":"NTFILE3dTedbs7UW4PvtWS","market":"us","size":39837},{"description":"","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/image03.jpg","primary":false,"translateUrl":"","linkName":"image03.jpg","type":"GRAPHIC","id":"NTFILE6oZ7PR6Hi2LAdgLm","market":"us","size":42023},{"description":"","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000115/image04.gif","primary":false,"translateUrl":"","linkName":"image04.gif","type":"GRAPHIC","id":"NTFILEGKes65iEakiQhxow","market":"us","size":16369}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Annual Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Annual Report","pubTime":"2026-02-26 13:00","pubTimestamp":1772082000,"title_zh":"Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20764217","market":"us","labels":[],"media":"sec.gov","original_id":"AN114036126006718-IONS","pdf_url":"","pub_time":1771995600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 8-K - Current report","symbol":"IONS","title":"Form 8-K - Current report","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000114036126006718/0001140361-26-006718-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EXHIBIT 99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000114036126006718/ef20066495_ex99-1.htm","primary":true,"translateUrl":"","linkName":"ef20066495_ex99-1.htm","type":"EX-99.1","id":"NTFILEAjncHKUJZVJcWsje","market":"us","size":453449},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000114036126006718/ef20066495_8k.htm","primary":false,"translateUrl":"","linkName":"ef20066495_8k.htm","type":"8-K","id":"NTFILE4EbFvBBofwVR9ggc","market":"us","size":27110},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000114036126006718/image0.jpg","primary":false,"translateUrl":"","linkName":"image0.jpg","type":"GRAPHIC","id":"NTFILEEbjzhraPvMs52yim","market":"us","size":24775}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2026-02-25 13:00","pubTimestamp":1771995600,"title_zh":"Form 8-K - Current report","summary_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20736638","market":"us","labels":[],"media":"sec.gov","original_id":"AN197248126000055-IONS","pdf_url":"","pub_time":1770958800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000055/0001972481-26-000055-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000055/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEcxtkJFmLxDjJ7zdi","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-02-13 13:00","pubTimestamp":1770958800,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20725617","market":"us","labels":[],"media":"sec.gov","original_id":"AN197248126000053-IONS","pdf_url":"","pub_time":1770786000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000053/0001972481-26-000053-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000053/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE4u1vBxnDywG632hL","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-02-11 13:00","pubTimestamp":1770786000,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20710094","market":"us","labels":[],"media":"sec.gov","original_id":"AN197248126000045-IONS","pdf_url":"","pub_time":1770354000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000045/0001972481-26-000045-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000045/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEEsmGvoF6Qg1qXrpG","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-02-06 13:00","pubTimestamp":1770354000,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20689097","market":"us","labels":[],"media":"sec.gov","original_id":"AN197248126000034-IONS","pdf_url":"","pub_time":1770008400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000034/0001972481-26-000034-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000034/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEYdwvVka1NYxh4DKL","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-02-02 13:00","pubTimestamp":1770008400,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20684335","market":"us","labels":[],"media":"sec.gov","original_id":"AN87401526000080-IONS","pdf_url":"","pub_time":1769822360000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/0000874015-26-000080-index.html","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000080/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE4G2EAAc52B5GGyhH","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-01-31 09:19","pubTimestamp":1769822360,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20684266","market":"us","labels":[],"media":"sec.gov","original_id":"AN87401526000086-IONS","pdf_url":"","pub_time":1769749200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000086/0000874015-26-000086-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000086/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE4AndyFDag3dJxK6P","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-01-30 13:00","pubTimestamp":1769749200,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20684263","market":"us","labels":[],"media":"sec.gov","original_id":"AN87401526000085-IONS","pdf_url":"","pub_time":1769749200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000085/0000874015-26-000085-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000085/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE2HXgz54sJ2gKJetN","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-01-30 13:00","pubTimestamp":1769749200,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20684255","market":"us","labels":[],"media":"sec.gov","original_id":"AN87401526000084-IONS","pdf_url":"","pub_time":1769749200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000084/0000874015-26-000084-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000084/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE42VYocLP9D8Hb6s6","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-01-30 13:00","pubTimestamp":1769749200,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20684248","market":"us","labels":[],"media":"sec.gov","original_id":"AN87401526000083-IONS","pdf_url":"","pub_time":1769749200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000083/0000874015-26-000083-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000083/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE4aqcE1TQaQhhUfqm","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-01-30 13:00","pubTimestamp":1769749200,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20684247","market":"us","labels":[],"media":"sec.gov","original_id":"AN87401526000082-IONS","pdf_url":"","pub_time":1769749200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000082/0000874015-26-000082-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000082/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEBSV9ABzU41fBuCf4","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-01-30 13:00","pubTimestamp":1769749200,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20684245","market":"us","labels":[],"media":"sec.gov","original_id":"AN87401526000081-IONS","pdf_url":"","pub_time":1769749200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000081/0000874015-26-000081-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000081/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE72XoC8DAG2eKZT3B","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-01-30 13:00","pubTimestamp":1769749200,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20684237","market":"us","labels":[],"media":"sec.gov","original_id":"AN87401526000078-IONS","pdf_url":"","pub_time":1769749200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000078/0000874015-26-000078-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000087401526000078/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEQZc8sejqCbBcHEyd","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-01-30 13:00","pubTimestamp":1769749200,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20654324","market":"us","labels":[],"media":"sec.gov","original_id":"AN197248126000027-IONS","pdf_url":"","pub_time":1769058000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"IONS","title":"Form 144 - Report of proposed sale of securities","titleType":"Proposed Sale Of Securities","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000027/0001972481-26-000027-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/874015/000197248126000027/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEHt4BbeVXuENxvhjp","market":"us","size":0}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Proposed Sale Of Securities","pubTime":"2026-01-22 13:00","pubTimestamp":1769058000,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0}],"pageSize":20,"totalPage":22,"pageCount":3,"totalSize":426,"code":"91000000","status":"200"}]}}