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Says Pelacarsen Heart Disease Drug Missed Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2665235141","media":"Dow Jones","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665235141?lang=en_us&edition=fundamental","pubTime":"2026-09-05 04:50","pubTimestamp":1788555000,"startTime":"0","endTime":"0","summary":"Novartis said a heart disease drug did not meet its primary endpoint in a Phase 3 study.The company on Friday said that the drug, pelacarsen, did not reduce the risk of cardiovascular events--including deaths, heart attacks, and strokes--compared to a placebo.The drug did succeed in lowering lipoprotein levels, Novartis said.\"These are not the results we hoped for, but they provide important evidence that advances scientific understanding of the relationship between Lp lowering and cardiovascular outcomes and may help inform future approaches to cardiovascular risk management,\" Chief Medical Officer Shreeram Aradhye said.Pelacarsen was initially discovered and developed by Ionis Pharmaceuticals, before Novartis exercised an option to license development and commercialization rights for the drug in 2019.Shares of Novartis declined 4.4% to $153.00 in after-hours trading on Friday. 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Stock Underperforms Friday When Compared to Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2665375351","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665375351?lang=en_us&edition=fundamental","pubTime":"2026-09-05 04:33","pubTimestamp":1788553980,"startTime":"0","endTime":"0","summary":"DJ Merck & Co. Inc. Stock Underperforms Friday When Compared To CompetitorsThis article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Merck & Co. Inc.  slid 1.32% to $150.33 Friday, on what proved to be an all-around poor trading session for the stock market, with the S&P 500 Index  falling 0.38% to 7,718.60 and Dow Jones Industrial Average  falling 0.51% to 53,414.25.The stock's fall snapped a three-day winning streak.Merck & Co. Inc. closed 4.20% below its 52-week high of $156.92, which the company achieved on August 25th.The stock underperformed when compared to some of its competitors Friday, as Johnson & Johnson  fell 1.15% to $275.23, Pfizer Inc.  fell 1.25% to $28.45, and Eli Lilly & Co.  fell 0.88% to $1,149.36.Trading volume  remained 5.9 million below its 50-day average volume of 10.1 M.Data source: Dow Jones Market Data, FactSet. Data compiled September 4, 2026.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999001440.SGD","SG9999015358.SGD","LU1037948541.HKD","LU0006306889.USD","LU1037948897.HKD","LU2433249047.HKD","LU1989772840.SGD","LU1093756325.SGD","LU2112291526.USD","LU2023250843.SGD","LU2361044949.HKD","TRUH","LU1917777945.USD","SG9999001176.SGD","SG9999014542.SGD","LU2125909247.SGD","LU0868494708.USD","LU2360032135.SGD","LU1069347547.HKD","PAWZ","LU2468319806.SGD","BK4007","LU0859254822.USD","IE00B4R5TH58.HKD","LU1923622614.USD","LU0980610538.SGD","IE00BJT1NW94.SGD","IE00BSNM7G36.USD","LU0106261372.USD","LU1585245621.USD","IE00B1BXHZ80.USD","BK4534","GDOC","BK4559","BK4588","SG9999002224.SGD","BK4585","LU0098860793.USD","IE0002141913.USD","LU2324357040.USD","LU2357627491.SGD","LU0234572021.USD","LU2106854487.HKD","LU0203347892.USD","PPH","SG9999001176.USD","HRTS","FTXH","LU2361044865.SGD","LU2125154778.USD","LU2089984988.USD","LU2361045086.USD","LU0648001328.SGD","LU0266013472.USD","SG9999015341.SGD","LU2023250504.SGD","LU0265550946.USD","BK4550","LU0861579265.USD","SG9999013999.USD","LU1699723380.USD","LU1066051225.USD","LU1929549753.HKD","BK4516","LU0122379950.USD","LU2125909593.SGD","LU1116320737.USD","LU0130517989.USD","IXJ","IHE","LU0320765646.SGD","LU1934455277.USD","LU0265550359.USD","LU0130102774.USD","MRK","SG9999014575.USD","BK4533","LU0203345920.USD","LU0823416689.USD","IE00BBT3K403.USD","FHLC","LU0868494617.USD","LU0238689110.USD","LU1291159041.SGD","LU1066051498.USD","LU1057294990.SGD","LU0689626769.HKD","IYH","LU2491050071.SGD","IE00BFTCPJ56.SGD","LU1162221912.USD","LU1941712348.USD","RXL","LU1430594728.SGD","VHT","SG9999014559.SGD","XLV","LU1093756168.USD","LU0965509101.SGD","LU1974910355.USD","LU1066051811.HKD","LU1934455863.HKD","IE000M9KFDE8.USD","LU1571399168.USD","IE00BLSP4452.SGD","LU0070302665.USD","LU0124676726.USD","LU0942090050.USD","LU1201861249.SGD","SGXZ57979304.SGD","LU0432979614.USD","LU2461242641.AUD","IE00BN8TJ469.HKD","LU1066053197.SGD","IE00BJJMRZ35.SGD","IE0009355771.USD","IE00B2B36J28.USD","LU1989771016.USD","LU2491050154.USD","LU0320765489.SGD","BMED","LU1934455194.USD","LU0211331839.USD","LU2491049909.HKD","IE00BLSP4239.USD","LU0965508806.USD","LU1035773651.USD","LU1941712264.USD","LU1032466523.USD","LU0477156953.USD","LU0985320562.USD","SG9999014567.USD","LU0965509010.AUD","LU0289739699.SGD","LU0965509283.SGD","LU0058720904.USD","LU1061106388.HKD","LU2125154935.USD","SG9999002232.USD","LU1023059063.AUD","JDOC","LU1116320901.HKD","LU1989772923.USD","LU1983299246.USD","LU0208291251.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2665513783","title":"AbbVie Inc. Stock Underperforms Friday When Compared to Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2665513783","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2665513783?lang=en_us&edition=fundamental","pubTime":"2026-09-05 04:31","pubTimestamp":1788553860,"startTime":"0","endTime":"0","summary":"DJ AbbVie Inc. Stock Underperforms Friday When Compared To CompetitorsThis article was automatically generated by MarketWatch using technology from Automated Insights.Shares of AbbVie Inc.  shed 1.44% to $256.46 Friday, on what proved to be an all-around grim trading session for the stock market, with the S&P 500 Index  falling 0.38% to 7,718.60 and Dow Jones Industrial Average  falling 0.51% to 53,414.25.This was the stock's second consecutive day of losses.AbbVie Inc. closed 4.12% below its 52-week high of $267.47, which the company achieved on July 29th.The stock demonstrated a mixed performance when compared to some of its competitors Friday, as Johnson & Johnson  fell 1.15% to $275.23, Pfizer Inc.  fell 1.25% to $28.45, and Amgen Inc.  fell 1.55% to $437.23.Data source: Dow Jones Market Data, FactSet. Data compiled September 4, 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Closes $10.9B Takeover of Apogee, Its Largest Deal Since 2019, With Earnings Lift Expected From 2032","url":"https://stock-news.laohu8.com/highlight/detail?id=1127014248","media":"Stock News","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1127014248?lang=en_us&edition=fundamental","pubTime":"2026-09-04 09:44","pubTimestamp":1788486257,"startTime":"0","endTime":"0","summary":"AbbVie (NYSE: ABBV) announced on Thursday that it has finalized its $10.9 billion acquisition of inflammation drug developer Apogee Therapeutics (NASDAQ: APGE). 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