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However, the year-to-date share price return of 29.51% and 1-year total shareholder 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It is the first drug approved in the U.S. that targets both proteins at once, though several other drugs already treat the disease. Vertex Pharmaceuticals is chasing a similar drug that also blocks both proteins, which the FDA is due to rule on later this year.-- The accelerated approval was based on an interim look at Vera's ongoing Phase 3 trial, before the study is complete. Patients on Trutakna saw a 46% drop in a urine-protein marker doctors use to track kidney damage. 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The deal has a total equity value of about $10 billion and is expected to close in Q3, the companies said.Shares of Crinetics almost doubled amid a surge in intraday trading volume to over 67.1 million from a daily average of roughly 1.30 million.MeiraGTx  has signed a deal under which Oberland Capital Management has agreed to invest up to $400 million in the company, including up to $375 million in non-dilutive capital for capped royalty payments on certain products and up to $25 million in equity, it said Tuesday.Shares jumped 8.2% following an increase in intraday trading volume to over 1.01 million from a daily average of about 987,000.Tvardi Therapeutics  said Tuesday its phase 1 study confirmed rapid prodrug conversion of TTI-109 to TTI-101, producing nearly identical plasma levels at molar-equivalent doses, and validating 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Pharmaceuticals' Acquisition of Crinetics Adds Rare-Disease Drugs, UBS Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2649934336","media":"MT Newswires Live","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2649934336?lang=en_us&edition=fundamental","pubTime":"2026-07-08 01:36","pubTimestamp":1783445763,"startTime":"0","endTime":"0","summary":"Vertex Pharmaceuticals'  planned $10 billion acquisition of Crinetics Pharmaceuticals  may prompt investor questions on the timing of the deal with several major clinical trial results already expected in early 2027, UBS Securities said Monday in a note.UBS said the deal adds two important rare-disease drugs: Palsonify, used to treat acromegaly, a condition caused by excess growth hormone, and atumelnant, now in late-stage testing for congenital adrenal hyperplasia, a disorder that affects hormone production.Vertex on Monday described the acquisition as a potential blockbuster with expected sales of more than $5 billion.The near-term focus will stay on rival cystic fibrosis data expected this summer, while Vertex's own 2027 trial results should provide additional catalysts, UBS said.UBS has a buy rating on Vertex stock with a $545 price target.Vertex shares fell 1% in Tuesday trading, and Crinetics declined 0.5%.Price: 524.45, Change: -5.14, Percent Change: 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Update: Healthcare","url":"https://stock-news.laohu8.com/highlight/detail?id=2649931153","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2649931153?lang=en_us&edition=fundamental","pubTime":"2026-07-08 01:01","pubTimestamp":1783443702,"startTime":"0","endTime":"0","summary":"Healthcare stocks rose Tuesday afternoon, with the NYSE Healthcare Index rising 1.6% and the State Street Health Care Select Sector SPDR ETF  adding 1.5%.The iShares Biotechnology ETF  climbed 1.7%.In corporate news, Vertex Pharmaceuticals  agreed to buy endocrine disease drugmaker Crinetics Pharmaceuticals  for a total equity value of about $10 billion. Crinetics shares surged 98%, and Vertex was down 0.5%.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IE0002141913.USD","LU2324357040.USD","IE00B894F039.SGD","CRNX","VRTX","LU0432979614.USD","BBH","LU1778281490.HKD","IE00B19Z3B42.SGD","LU2237438978.USD","BK4533","IE00B4R5TH58.HKD","SG9999013999.USD","SG9999001176.SGD","BK4581","IE0002270589.USD","IE00BJT1NW94.SGD","LU0029874061.USD","LU1585245621.USD","IDNA","HCSG","IE0009355771.USD","IE00BJJMRZ35.SGD","LU0128526141.USD","SGXZ57979304.SGD","LU2456880835.USD","IE00B2B36J28.USD","LU2462157665.USD","IBB","PBE","BIB","LU2362541513.USD","LU1093756168.USD","BK4588","LU1430594728.SGD","LU1674673428.USD","LU0823416689.USD","BK4532","LABU","XBI","IBBQ","LU0061475181.USD","XLV","LU0109394709.USD","IE00BFTCPJ56.SGD","LU1069344957.HKD","LU2362540622.SGD","LU0289739699.SGD","LU0320765992.SGD","IE00B19Z9P08.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2649931580","title":"Crinetics downgraded to Market Perform from Outperform at Citizens","url":"https://stock-news.laohu8.com/highlight/detail?id=2649931580","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2649931580?lang=en_us&edition=fundamental","pubTime":"2026-07-08 00:40","pubTimestamp":1783442416,"startTime":"0","endTime":"0","summary":"Citizens analyst Jonathan Wolleben downgraded Crinetics (CRNX) to Market Perform from Outperform after Vertex Pharmaceuticals (VRTX) agreed to 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It also offers a clinically compelling program with multi-blockbuster potential in atumelnant, a possible treatment for congenital adrenal hyperplasia and Cushing's Syndrome, the analysts add. \"Together, these assets give Vertex a foothold in endocrinology--a fifth therapeutic area for the company,\" they write. \"We see clear strategic rationale: addition of solid, innovative science, with atumelnant carrying relatively modest binary risk.\" Vertex shares are roughly flat in premarket trading Tuesday, while Crinetics shares double.  Dow Jones NewswiresJuly 07, 2026 09:19 ET Copyright  2026 Dow Jones & Company, 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Sees Over $5 Billion Peak Sales Potential From Crinetics Assets","url":"https://stock-news.laohu8.com/highlight/detail?id=2649498051","media":"Benzinga","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2649498051?lang=en_us&edition=fundamental","pubTime":"2026-07-07 20:24","pubTimestamp":1783427040,"startTime":"0","endTime":"0","summary":"Vertex to acquire Crinetics for $10 billion, adding approved acromegaly drug Palsonify and late-stage CAH candidate atumelnant to its rare disease portfolio.","market":"us","thumbnail":"https://cdn.benzinga.com/cdn-cgi/image/width=260,format=auto,quality=85/files/images/story/2026/07/07/Vertex-Pharmaceuticals-Incorporated--All.jpg","type":0,"news_type":0,"thumbnails":["https://cdn.benzinga.com/cdn-cgi/image/width=260,format=auto,quality=85/files/images/story/2026/07/07/Vertex-Pharmaceuticals-Incorporated--All.jpg"],"rights":{"source":"benzinga_hot_news","url":"https://www.benzinga.com/m-a/26/07/60302092/vertex-sees-over-5-billion-peak-sales-potential-from-crinetics-assets","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/m-a/26/07/60302092/vertex-sees-over-5-billion-peak-sales-potential-from-crinetics-assets","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"benzinga_hot_news","symbols":["SKIS","VERX","VRTX"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2649823509","title":"This Biotech Stock is Soaring 99% After Vertex Agrees to Takeover Deal","url":"https://stock-news.laohu8.com/highlight/detail?id=2649823509","media":"Dow Jones","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2649823509?lang=en_us&edition=fundamental","pubTime":"2026-07-07 19:33","pubTimestamp":1783423980,"startTime":"0","endTime":"0","summary":"Crinetics Pharmaceuticals stock was surging on Tuesday after Vertex Pharmaceuticals said it had agreed to buy the biotech for $10 billion.Shares of Crinetics jumped 99% to $83.69 ahead of the opening 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Remains a Buy on Vertex Pharmaceuticals (VRTX)","url":"https://stock-news.laohu8.com/highlight/detail?id=2649984413","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2649984413?lang=en_us&edition=fundamental","pubTime":"2026-07-07 19:15","pubTimestamp":1783422959,"startTime":"0","endTime":"0","summary":"Citi analyst Geoff Meacham maintained a Buy rating on Vertex Pharmaceuticals today and set a price target of $585.00. Meacham covers the Healthcare...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/citi-remains-a-buy-on-vertex-pharmaceuticals-vrtx-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/citi-remains-a-buy-on-vertex-pharmaceuticals-vrtx-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IBBQ","SG9999013999.USD","LU0889565916.HKD","LU1035775433.USD","LU1093756325.SGD","IE0009355771.USD","LU1069344957.HKD","LU0432979614.USD","IE00B894F039.SGD","LU2324357040.USD","LU2362541273.HKD","IE00BZ9MQY76.HKD","LU2237438978.USD","BK4533","BK4532","BK4581","LU0234570918.USD","LU1778281490.HKD","LU1815336091.USD","SG9999001176.SGD","IE00BJJMRZ35.SGD","LU1430594728.SGD","LU2362541513.USD","VRTX","BK4139","LU0417517546.SGD","IE00B4R5TH58.HKD","XBI","BBH","IDNA","IBB","LU0079474960.USD","LU1093756168.USD","BK4023","IE00B19Z9Z06.USD","IE00B19Z9P08.USD","LU0109394709.USD","PBE","LU2417539215.USD","VERX","XLV","BK4585","LU0757428866.USD","LU0823416689.USD","IE0002141913.USD","LABU","LU2236285917.USD","BK4567","BIB","LU2462157665.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2649981771","title":"Vertex Pharmaceuticals is Maintained at Underperform by Baird","url":"https://stock-news.laohu8.com/highlight/detail?id=2649981771","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2649981771?lang=en_us&edition=fundamental","pubTime":"2026-07-07 19:04","pubTimestamp":1783422240,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/VRTX/analyst-ratings(END) Dow Jones NewswiresJuly 07, 2026 07:04 ET","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["VRTX","VERX"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2649198131","title":"Baird Adjusts Price Target on Vertex Pharmaceuticals to $350 From $330","url":"https://stock-news.laohu8.com/highlight/detail?id=2649198131","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2649198131?lang=en_us&edition=fundamental","pubTime":"2026-07-07 18:38","pubTimestamp":1783420709,"startTime":"0","endTime":"0","summary":"Vertex Pharmaceuticals (VRTX) has an average rating of overweight and mean price target of $555, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research fr","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["VRTX","VERX"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":10,"pageCount":9,"totalSize":200,"code":"91000000","status":"200"}]}}